Connective tissue

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Unknown (4603)
Transcriptomics (1199)
Genomics (558)
Proteomics (157)
Metabolomics (22)
Genomic (13)
Other (12)
Clinical (4)
Methylation profiling (4)
Multiomics (1)

Organisms

Homo sapiens (826)
Mus musculus (439)
Rattus norvegicus (54)
Bos taurus (27)
Gallus gallus (15)
Sus scrofa (10)
Danio rerio (10)
Escherichia coli (10)
Ambystoma mexicanum (8)
Spodoptera frugiperda (8)
Triticum aestivum (8)
Capra aegagrus (6)
Cricetulus griseus (6)
Zea mays (5)
Salmo salar (5)
Macaca mulatta (4)
Canis lupus familiaris (4)
Arabidopsis thaliana (3)
Oncorhynchus mykiss (3)
Ovis aries (3)
Equus caballus (3)
Streptococcus pneumoniae (2)
Xenopus laevis (2)
Macaca fascicularis (2)
Oryctolagus cuniculus (2)
synthetic construct (2)
Capra hircus (2)
Trichoderma reesei (1)
Tetraodon nigroviridis (1)
Staphylococcus aureus (1)

Organisms

Homo sapiens (148)
Mus musculus (121)
Rattus norvegicus (19)
Danio rerio (8)
Ambystoma mexicanum (7)
Bos taurus (6)
Gallus gallus (6)
Equus caballus (4)
Salmo salar (4)
Ovis aries (4)
Chaenocephalus aceratus (2)
Anolis carolinensis (2)
Sus scrofa (2)
Cervus canadensis (1)
Polypterus senegalus (1)
Eublepharis macularius (1)
Megalobrama amblycephala (1)
Xenopus tropicalis (1)
Macaca fascicularis (1)
Tetraodon nigroviridis (1)
Oryctolagus cuniculus (1)
Equus asinus (1)
Felis catus (1)
Canis lupus familiaris (1)
Mus musculus x Rattus norvegicus (1)
Oryzias latipes (1)
mouse gut metagenome (1)
unidentified (1)

Repository

biostudies-arrayexpress (979)
ENA (395)
geo (297)
EGA (116)
pride (68)
MassIVE (43)
MetaboLights (22)
jPOST (16)
dbGaP (13)
GPMDB (4)
iProX (4)
PanoramaPublic (4)
ExpressionAtlas (3)
PeptideAtlas (1)

Tissue

Cell culture (11)
Connective tissue (7)
Skin (5)
Lung (4)
Liver (4)
Pancreas (3)
Brain (2)
Musculature (1)
Hematopoietic system (1)
Peripheral nervous system (1)
Vulva (1)
Mucosa (1)
Bile duct (1)
Bone (1)
Placenta (1)
Gall bladder (1)
Uterine cervix (1)
Breast (1)
Esophagus (1)
Large intestine (1)
Stomach (1)
Ovary (1)
Uterus (1)
Urinary bladder (1)
Prostate gland (1)
Adrenal gland (1)
Thyroid gland (1)
Testis (1)
Kidney (1)
Others (1)

Disease

Fibrosarcoma (3)
Osteosarcoma (2)
Anaplastic astrocytoma (1)
Carcinoma (1)
Chondrosarcoma (1)
Hodgkins lymphoma (1)
Mesothelioma (1)
Acute myelomonocytic leukemia (1)
Bladder carcinoma (1)
Diffuse large B-cell lymphoma (1)
Bone neoplasm (1)
Acute myeloid leukemia (1)
Ewing sarcoma (1)
Chronic myelogenous leukemia (1)
Papillary lung adenocarcinoma (1)
Cervical carcinoma (1)
Neuroblastoma (1)
Eosinophilic leukemia (1)
Large cell lung carcinoma (1)
Salivary gland neoplasm (1)
Rhabdomyosarcoma (1)
Vulvar carcinoma (1)
Acute lymphoblastic leukemia (1)
Ovarian granulosa tumour (1)
Hairy cell leukemia (1)
Gallbladder adenocarcinoma (1)
Essential thrombocythemia (1)
Synovial sarcoma (1)
Esophageal squamous cell carcinoma (1)
Diffuse large B cell lymphoma (1)

Technology Type

Mass Spectrometry (68)
Shotgun proteomics (41)
Mass spectrometry assay (11)
Mass spectrometry (10)
Data-independent acquisition (10)
Bottom-up proteomics (8)
Illumina HiSeq 2000 (7)
SWATH MS (5)
Data-dependent acquisition (4)
Gel-based experiment (4)
Affinity purification coupled with mass spectrometry proteomics (3)
ILLUMINA, Illumina HiSeq 2000 (2)
Top-down proteomics (2)
Illumina MiSeq, Illumina HiSeq 2000, ILLUMINA (1)
NextSeq 500, ILLUMINA (1)
Nanostring cancer pathway, Nanostring Cancer Immune, ILLUMINA, Affymetrix GeneChipÂ® Human Transcriptome Array 2.0, Illumina HiSeq 4000 (1)
NextSeq 500, Illumina HiSeq 2500, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 4000, Illumina HiSeq 2500 (1)
Illumina HiSeq 2500, ILLUMINA (1)
Aperio (1)
Illumina HiSeq 2000, Infinium HumanMethylation450 BeadChip (1)
Illumina HiSeq 2000, ILLUMINA, Illumina HiSeq 2500 (1)
Illumina HiSeq 2500 (1)
NMR spectroscopy (1)
All-ion fragmentation (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
HDMSE (1)
MSE (1)

Instrument Platform

Illumina NovaSeq 6000 (26)
Illumina HiSeq 2500 (23)
NextSeq 500 (14)
Illumina HiSeq 4000 (13)
Illumina HiSeq 2000 (9)
Illumina MiSeq (4)
Axon GenePix 4000B scanning hardware (3)
Bio-Rad CFX96 Real-time System (2)
Scanning hardware (2)
None (2)
Illumina HiSeq 1500 (2)
Illumina HiSeq 3000 (2)
Using NEBNext Ultra II DNA Library (1)
Genechip Scanner 3000 7G (1)
Thermal cycler, Magnetic stand / beads, Pipettes and tips, Microcentrifuge tubes, Plate shaker (1)
Centrifuge, Pipettes and tips, Agilent 2100 Bioanalyzer, NanoDrop spectrophotometer, Vortex mixer (1)
Liquid nitrogen, -80°C freezer, Surgical tools (scalpels, forceps), Sample tubes / cryovials (1)
Described in protocol (1)
Nikon Eclipse Ti2 with brightfield and fluorescence capacity (TRITC) (1)
Leica Biosystems Cryostat (1)
Nanostring GeoMx® spatial profiler (1)
Thermo Fisher (1)
10X Genomics Chromium v3.1 with multiplexing kit (1)
BD LSRFortessa (1)
MACS Whole Skin Dissociation Kit (1)
10x Chromium (1)
G2565BA DNA microarray scanner (1)
Qubit instrument, DNA HS kit (1)
High Sensitivity DNA kit (1)
BioRad SureCell (1)

Publication Date

2010 (123)
2013 (117)
2014 (107)
2012 (105)
2015 (101)
2011 (100)
2016 (83)
2025 (78)
2009 (72)
2008 (72)
2023 (60)
2022 (57)
2021 (54)
2020 (50)
2026 (43)
2024 (39)
2019 (38)
2018 (35)
2007 (33)
2017 (31)
2006 (18)
2005 (10)
2004 (4)
2003 (1)
2027 (1)

UNIPROT ID/AC

A0A024RC46 (1)
A0A075B6P5 (1)
A0A087WT59 (1)
A0A087WTX5 (1)
A0A087WVW2 (1)
A0A087WYL9 (1)
A0A087X130 (1)
A0A087X1V9 (1)
A0A0A0MS07 (1)
A0A0A0MS51 (1)
A0A0B4J1V0 (1)
A0N5G5 (1)
A2BFH1 (1)
A2IPI2 (1)
A2IPI5 (1)
A2J422 (1)
A2J423 (1)
A2JA19 (1)
A2NB46 (1)
A2NI60 (1)
A2NUT2 (1)
A2NXP9 (1)
A2NYQ9 (1)
A2NZ55 (1)
A4F255 (1)
A5A3E0 (1)
A6NHL2 (1)
A6NNZ2 (1)
A7E2Y1 (1)
B1AHL2 (1)

ENSEMBL ID

ENSG00000170477 (1)

CHEBI ID

CHEBI:16113 (3)
CHEBI:16977 (3)
CHEBI:15428 (3)
CHEBI:4167 (3)
CHEBI:15741 (3)
CHEBI:17115 (3)
CHEBI:17203 (3)
CHEBI:18050 (3)
CHEBI:16015 (3)
CHEBI:32816 (3)
CHEBI:16414 (3)
CHEBI:17191 (3)
CHEBI:15603 (3)
CHEBI:17895 (3)
CHEBI:17295 (3)
CHEBI:30813 (2)
CHEBI:22605 (2)
CHEBI:48300 (2)
CHEBI:8337 (2)
CHEBI:27389 (2)
CHEBI:30805 (2)
CHEBI:17553 (2)
CHEBI:33508 (2)
CHEBI:48430 (2)
CHEBI:16997 (2)
CHEBI:16708 (2)
CHEBI:15729 (2)
CHEBI:4139 (2)
CHEBI:17924 (2)
CHEBI:28875 (2)

Metabolite Name

L-Aspartic acid (4)
L-Proline (4)
L-Serine (4)
L-Phenylalanine (4)
D-Glucose (3)
L-Alanine (3)
Erucic acid (3)
Succinic acid (3)
L-Histidine (3)
L-Glutamic acid (3)
L-Tryptophan (3)
L-Glutamine (3)
Adenine (3)
Creatinine (3)
Creatine (3)
L-Valine (3)
L-Isoleucine (3)
L-Leucine (3)
L-Tyrosine (3)
PI(39:5) (2)
PE(36:1) (2)
PE(36:3) (2)
PS(42:2) (2)
PS(42:1) (2)
PS(40:5) (2)
PS(40:2) (2)
PS(40:1) (2)
PS(38:5) (2)
PS(38:3) (2)
PS(38:1) (2)

First Public Date

2014 (71)
2025 (57)
2024 (49)
2026 (39)
2023 (37)
2021 (30)
2022 (28)
2019 (20)
2020 (18)
2018 (14)
2017 (12)
2015 (11)
2013 (5)
2016 (4)

Study status

Terminated (1)
Not yet recruiting (1)
Recruiting (1)
Completed (1)

Study type

Transcription profiling by array (718)
RNA-seq of coding RNA (85)
Comparative genomic hybridization by array (23)
ChIP-seq (22)
Unknown experiment type (20)
RNA-seq of coding RNA from single cells (15)
Methylation profiling by array (11)
Genotyping by array (9)
Animal - High-throughput sequencing (6)
Other (6)
MicroRNA profiling by array (6)
Methylation profiling by high throughput sequencing (6)
ChIP-chip by array (5)
Transcription profiling by RT-PCR (5)
Spatial transcriptomics by high-throughput sequencing (4)
RNA-seq of total RNA (4)
RNA-seq of non coding RNA (4)
ChIP-chip by tiling array (3)
Human - High-throughput sequencing (3)
High-throughput sequencing (3)
RNAi profiling by array (3)
Baseline (2)
Human - Methylation microarray (2)
Cell line - High-throughput sequencing (2)
DNA-seq (2)
Proteomic profiling by array (2)
Transcription profiling by SAGE (1)
Cell line - Single-cell sequencing (1)
RNA-seq of non coding RNA from single cells (1)
Animal - One-color microarray (1)

Release Date

2022 (564)
2023 (494)
2025 (462)
2021 (450)
2020 (418)
2024 (367)
2019 (328)
2018 (272)
2014 (268)
2015 (264)
2016 (253)
2017 (238)
2013 (213)
2010 (182)
2012 (172)
2011 (169)
2009 (117)
2008 (106)
2026 (70)
2007 (56)
2006 (43)
2005 (24)
2002 (13)
2003 (11)
2001 (8)
2004 (6)
2000 (6)
1998 (3)
1997 (3)
1999 (2)

Lab affiliation

Department of Cellular Immunology, German Cancer Research Center Heidelberg, Germany (2)
Institute of Lung Biology and Disease and Comprehensive Pneumology Center, Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, German (2)
"Philip Morris R&D, Neuchatel, Switzerland" (1)
8Clinical Protein Science & Imaging, Biomedical Centre, Department of Biomedical Engineering, Lund University, Lund, Sweden (1)
Basilbiotech, Incheon 22002, Republic of Korea. (1)
Biomedical Engineering department, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States (1)
CECAD Excellent in Aging Research Cluster of Excellence for Aging Research at the University of Cologne Joseph-Stelzmann-Straße 26 50931 Cologne (1)
CMB - Center for Molecular Biomedicine Hans-Knöll-Str. 2 07745 Jena (1)
Cardiovascular department, Yale University (1)
Centre de Recherche des Cordeliers, Sorbonne Université, INSERM, Université de Paris, Oral Molecular Pathophysiology, F-75006, France (1)
Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, 3168, Australia. (1)
Cleveland Clinic (1)
Clinical and Diagnostic Immunology, Department Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium (1)
Comparative Biomedical Sciences Royal Veterinary College Royal College Street London NW1 0TU (1)
Departamento de Produção Animal Instituto Superior de Agronomia Tapada da Ajuda 1349-017 Lisboa Portugal (1)
Department of Biochemistry and Molecular Biology, Complex Carbohydrate Research Center, The University of Georgia, U.S.A. (1)
Department of Biochemistry and Molecular Biology, School of Life Sciences, Central South University, No. 172, Tongzipo road, Yuelu District, Changsha 410013, Hunan Province, China (1)
Department of Biological Chemistry, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA (1)
Department of Biotechnology St Aloysius (Deemed to be University) Mangalore – 575 003, Karnataka, India. (1)
Department of Diagnosis and Surgery, School of Dentistry at Araraquara, Sao Paulo State University - UNESP, Araraquara, São Paulo, Brazil. (1)
Department of Experimental Ophthalmology, Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckstr. 1, 55131 Mainz, Germany Phone: + 49 6131 17 3328 Fax: + 49 06131 4970563 (1)
Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands (1)
Department of Molecular Biology and Genetics, Aarhus University, Denmark (1)
Department of Molecular Medicine and Surgery Center for Molecular Medicine, Karolinska Institutet (1)
Department of Musculoskeletal Biology Institute of Ageing and Chronic Disease University of Liverpool (1)
Department of Pharmacology, Soochow University (1)
Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC, 29407 Department of Neurosurgery, Medical University of South Carolina, Charleston, SC, 29407 (1)
Division of Clinical Protein Science & Imaging, Department of Clinical Sciences (Lund), Department of Biomedical Engineering, Lund University, Lund, Sweden (1)
Dr. Rolf M. Schwiete Osteoarthritis Research Unit, Department of Trauma Surgery and Orthopedics, University Hospital, Goethe University, Frankfurt, Germany (1)
ETH Zurich, Switzerland (1)

Location

United States (2)
India (1)
Australia (1)

Keyword

Neglected Diseases (1)
Orphan Diseases (1)
Rare Disease Research (1)
Registries (1)
Batten Disease (1)
Mucolipidosis IV (1)
Undiagnosed (1)
Uncommon Disease (1)
Hypersomnia (1)
Marinesco-Sjogren Syndrome (1)
4p-/Wolf-Hirschhorn Syndrome (1)
Wiedermann-Steiner Syndrome (1)
Hemophagocytic Lymphohistiocytosis (HLH) (1)
Behcet’s Disease (1)
Jansen metaphyseal chondrodysplasia (1)
Chronic recurrent multifocal osteomyelitis (CRMO) (1)
Hereditary Sensory and Autonomic Neuropathy (1)
Nephropathic infantile cystinosis (1)
Ocular cystinosis (1)
Spinal Bulbar Muscular Atrophy (SBMA) (1)
Mucolipidosis (1)
Mitochondrial aminoacyl-tRNA synthetases (Mt-aaRS Disorders) (1)
Shine Syndrome (1)
Intestinal Bromhidrosis Syndrome (1)
Autosomal recessive extra oral halitosis (1)
CACNA1H mutation (1)
Dimethylglycine dehydrogenase deficiency (1)
Solid Organ Cancers (1)
Natural History (1)
Solid Organ Cancer (1)

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RNAseq of subepithelial connective tissue grafts obtained at different location and depth in the human palate

Aim: Identify set of genes, whose expression is dependent on the graft location in the patient’s palate (anterior vs. posterior) and depth of harvest (superficial vs. deep). The mRNA-Seq contains 64 human samples. The samples represent connective tissue grafts (CTGs) harvested at different locations...

ORGANISM(S): Homo sapiens

2023-12-13 | E-MTAB-13141 | biostudies-arrayexpress

Analysis of colorectal adenocarcinoma tissue samples by DESI mass spectrometry imaging

Ex vivo colorectal adenocarcinoma samples were analysed by desorption electrospray ionisation using an Orbitrap mass spectrometer. The samples were analysed in negative mode over the m/z range 600-1000. Some of the samples presented in this dataset were analysed as part of [1]. The study makes avail...

2016-04-28 | MTBLS289 | MetaboLights

Mouse Brown Adipose Tissue Lipidomics under Cold and Dietary Fat Interventions

This study investigates lipidomic remodeling in mouse brown adipose tissue under a 2 × 3 experimental design involving environmental condition and dietary fatty acid composition. Mice were maintained at room temperature with ad libitum feeding or exposed to 4°C cold conditions with 70% calorie restr...

2026-06-01 | MTBLS14642 | MetaboLights

RNA-seq of blood from donors with connective tissue diseases in the Lupus Extended Phenotype Cohort

The connective tissue diseases (CTDs) are group of inflammatory disorders with overlapping clinical and serological manifestations. We have undertaken Lupus Extended Phenotype (LEAP) study in of a cohort of adult patients with CTDs, namely systemic lupus erythematosus, Sjogren's syndrome, mixed and ...

ORGANISM(S): Homo sapiens

2019-06-05 | E-MTAB-7080 | biostudies-arrayexpress

Proteome profiles of skeletal muscle connective tissue: Influence of aging and physical training

Both aging and physical activity can influence the amount of connective tissue in skeletal muscle, but the impact of these upon specific extracellular matrix (ECM) proteins in skeletal muscle is unknown. We investigated the proteome profile of connective tissue in skeletal muscle by label-free prote...

ORGANISM(S): Mus musculus (Mouse)

2023-04-27 | PXD036532 | Pride

functional biomarker which could be used to predict connective healing based on an Achilles Tendon Model

Healing process after connective tissues (CT) injury is complex but important as CT are critical for human moving, and patient outcome of CT injured patients is protracted with high individual variation. Specific markers which could be used for healing prognosis will be great help to monitor patient...

ORGANISM(S): Homo sapiens (Human)

2023-05-10 | PXD033163 | Pride

Ms Connective tissue Healing Fibroblast Eef2 Biomarker

Rac1-Induced Connective Tissue Growth Factor regulates Connexin 43 and N-Cadherin Expression in Atrial Fibrillation

Objectives: We studied the signal transduction of atrial structural remodelling that contributes to the pathogenesis of atrial fibrillation (AF). Backround: Fibrosis is a hallmark of arrhythmogenic structural remodelling but the underlying molecular mechanisms are incompletely understood. Methods: W...

ORGANISM(S): Homo sapiens

2010-02-21 | E-GEOD-14975 | biostudies-arrayexpress

The essential role of connective-tissue cells during axolotl limb regeneration [Agilent]

PRJNA1249071 | ENA

Induction of muscle-related gene expression in loose connective tissue fibroblasts in response to static tissue stretch

Current knowledge of mechanically-induced regulation of gene expression in fibroblast is mostly based on experiments using prolonged cyclical stretching of either cultured cells or load-bearing connective tissues such as tendons and ligaments. In this study, we have examined the effect of static ti...

ORGANISM(S): Mus musculus

2011-05-08 | E-GEOD-11371 | biostudies-arrayexpress

Epigenome analysis of adipose/connective tissue from thyroid-associated ophthalmopathy

PRJNA732301 | ENA

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