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ProteomicsProteomic shift in mouse embryonic fibroblasts Pfa1 during ML210-induced ferroptosis
This report provides data on ferroptosis induced proteomic response in immortalized mouse embryonic fibroblasts which are 4-OH-TAM-inducible Gpx4−/− (referred to as Pfa1 cells). Pfa1 cells are a valuable, widespread and well characterized model for ferroptosis research. We used ML210 (SML0521, Sigma...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-10 | PXD041327 | Pride
Proteomics Mouse embryonic fibroblasts Ferroptosis Ml210 Erastin Glutathione peroxidase 4 Pfa1 Cell death 
ProteomicsProteomic shift in mouse embryonic fibroblasts Pfa1 during L-Buthionine-sulfoximine (BSO) induced ferroptosis
This report provides data on ferroptosis induced proteomic response in immortalized mouse embryonic fibroblasts which are 4-OH-TAM-inducible Gpx4−/− (referred to as Pfa1 cells). Pfa1 cells are a valuable, widespread and well characterized model for ferroptosis research. We used L-Buthionine-sulfoxim...
ORGANISM(S): Mus musculus (Mouse) 
2023-04-12 | PXD041415 | Pride
Bso Proteomics Mouse embryonic fibroblasts Ferroptosis Erastin Glutathione peroxidase 4 L-buthionine-sulfoximine Pfa1 Cell death 
ProteomicsProteomic response on ferroptosis induction via GPX4 KO in mouse embryonic fibroblasts
In the present study, we report proteome data of mouse embryonic fibroblasts (MEF cells) and immortalized mouse embryonic fibroblasts which are 4-OH-TAM-inducible Gpx4−/− (Pfa1 cells). Ferroptosis in Pfa1 cells was induced with Tamoxifen (Tam) addition and three timepoints were collected: 0h, 24h an...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2023-04-12 | PXD040094 | Pride
Proteomics Mouse embryonic fibroblasts Ferroptosis Glutathione peroxidase 4 Pfa1 Cell death 
ProteomicsProteomic shift in mouse embryonic fibroblasts Pfa1 during erastin-induced ferroptosis
This report provides data on ferroptosis induced proteomic response in immortalized mouse embryonic fibroblasts which are 4-OH-TAM-inducible Gpx4−/− (referred to as Pfa1 cells). Pfa1 cells are a valuable, widespread and well characterized model for ferroptosis research. In the first part of this ba...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-11 | PXD041463 | Pride
Proteomics Ferroptosis Mouse embryonic fibroblasts Erastin Glutathione peroxidase 4 Liproxtatin-1 Pfa1 Cell death 
TranscriptomicsKnockout of GPx4 gene in mouse keratinocyte
Comparative analysis of gene expression in cultured primary keratinocytes isolated from newborn control (K14-cre; GPx4fl/+) and knockout (K14-cre; GPx4fl/fl) mice. Selenoproteins are essential for skin function, as targeted abolition of selenoproteins in epidermal tissue results in newborn mice mani...
ORGANISM(S): Mus musculus 
2012-12-06 | E-GEOD-34215 | biostudies-arrayexpress
UnknownDirect Detection and Quantification of Neoantigens.
Not available
S-EPMC6825591 | biostudies-literature
TranscriptomicsIdentification and successful negotiation of a metabolic checkpoint in direct neuronal reprogramming
Despite the widespread interest in direct neuronal reprogramming, the mechanisms underpinning fate conversion remain largely unknown. Our study revealed a critical time point after which cells either successfully convert into neurons or succumb to cell death. Co-transduction with Bcl-2 greatly impro...
ORGANISM(S): Mus musculus 
2016-06-29 | E-GEOD-70921 | biostudies-arrayexpress
MetabolomicsGNPS - Targeting FSP1 triggers ferroptosis in lung cancer
Raw mass spectrometry data were acquired via LC-MS to quantify oxidized lipids and Coenzyme Q9 (CoQ9) in mouse lung tumor and cell line samples. A Parallel Reaction Monitoring (PRM) strategy was employed for oxidized lipids, while a Data-Dependent Acquisition (DDA) method was used for CoQ9.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-08-19 | MSV000098883 | GNPS
UnknownEndogenous incretin levels and risk of first incident cancer: a prospective cohort study.
Not available
S-EPMC9825393 | biostudies-literature
ProteomicsA non-canonical vitamin K cycle is a potent ferroptosis suppressor
Raw files corresponding to LC-MS-based relative quantification of oxidized lipids in Pfa1 cells and mouse liver samples subjected to ferroptosis. Data were acquired in parallel reaction monitoring (PRM) MS/MS mode.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-05-19 | MSV000089489 | MassIVE
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