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TranscriptomicsTranscription profiling of human T lymphocytes from patients with hypogammaglobulinemia of unknown cause (CVID) vs. hypogammaglobulinemia of known cause (XLA) and vs. healthy controls
Comparison of gene expression in T lymphocytes from patients with hypogammaglobulinemia of unknown cause (CVID), patients with hypogammaglobulinemia of known cause (XLA) and healthy controls
ORGANISM(S): Homo sapiens 
2004-07-18 | E-MEXP-76 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiles of CD21low B cells in Common Variable Immunodeficiency
The homeostasis of circulating B cell subsets in the peripheral blood of healthy adults is well regulated, but in disease it can be severely disturbed. Thus, a subgroup of patients with common variable immunodeficiency (CVID) presents with an extraordinary expansion of an unusual B cell population c...
ORGANISM(S): Homo sapiens 
2009-07-30 | E-GEOD-17269 | biostudies-arrayexpress
ProteomicsDistinct Proteomic and Transcriptomic Profiles in T-cells and Monocytes in Patients with Common Variable Immunodeficiency.
A large subgroup of Common Variable Immunodeficiency (CVID) patients has autoimmune and inflammatory complications (CVIDCOMP), associated with T cell and monocyte pathology. This dataset comprises untargeted proteomic analyses of CD3+ T cells and CD14+ monocytes isolated from patients with CVID, CVI...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD063397 | Pride
Microbiota Iga Tract Disease Rna Proteomics Gut Microbiome Duodenum Sequencing Gastrointestinal Celiac Cvid Primary Immunodeficiency 
ProteomicsDuodenal inflammation in common variable immunodeficiency has altered transcriptional response to viruses
A substantial proportion of common variable immunodeficiency (CVID) patients has duodenal inflammation of largely unknown etiology. However, because of its histologic similarities with celiac disease, gluten sensitivity has been proposed as a potential mechanism. We aimed to elucidate the role of th...
ORGANISM(S): Homo sapiens (Human) 
2025-04-29 | PXD063461 | Pride
Microbiota Iga Tract Disease Rna Proteomics Gut Microbiome Duodenum Sequencing Gastrointestinal Celiac Cvid Primary Immunodeficiency 
GenomicAntibody Repertoires in CVID

The data consist of the DNA sequences of antibody gene rearrangements from peripheral blood human B cells of subjects with Common Variable Immune Deficiency (CVID) and healthy controls subjects.

phs000934 | dbGaP
GenomicsGut Microbiota Alterations in CVID
Bacterial but not fungal gut microbiota alterations are associated with common variable immunodeficiency (CVID) phenotype
PRJEB32265 | ENA
GenomicsGene expression in duodenal biopsy samples from CVID enteropathy patients and healthy controls
Gene expression in duodenal biopsy samples from CVID enteropathy patients and healthy controls
PRJNA784599 | ENA
GenomicsGene expression in CD21low and CD21pos B cells from CVID patients
Gene expression in CD21low and CD21pos B cells from CVID patients
PRJNA623360 | ENA
TranscriptomicsGene expression in duodenal biopsy samples from CVID enteropathy patients and healthy controls
A subgroup of CVID patients presents with gastrointestinal complications (enteropathy), which manifests in the duodenum as celiac like-diese ase. CVID enteropathy patients can present with severe histopathology in form of villous atrophy (CVID VA) or without VA (CVID noVA). RNAseq data from CVID VA ...
ORGANISM(S): Homo sapiens 
2023-02-10 | GSE189820 | GEO
UnknownMonogenic Common Variable Immunodeficiency (Mo-CVID) Score for Optimizing the Genetic Diagnosis in Pediatric CVID Cohort.
Not available
S-EPMC11905875 | biostudies-literature
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