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TranscriptomicsFungenES: FunGenES_UKOE-4: Functional characterization and transcriptome analysis of embryonic stem cells-derived contractile smooth muscle cells
This experiment is part of the FunGenES project (FunGenES - Functional Genomics in Embryonic Stem Cells partially funded by the 6th Framework Programme of the EuropeanUnion, http://www.fungenes.org). The experiment was conducted at University of Cologne, Cologne, Germany. Goal of the experiment is a...
ORGANISM(S): Mus musculus 
2011-02-25 | E-TABM-1123 | biostudies-arrayexpress
TranscriptomicsConstitutively active RhoA (RhoAV14) expression and regulation of acqeous humor outflow dynamics
Impaired drainage of aqueous humor through the trabecular meshwork (TM) culminating in increased intraocular pressure is a major risk factor for glaucoma, a leading cause of blindness worldwide. Regulation of aqueous humor drainage through the TM, however, is poorly understood. The role of RhoA GTPa...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-9288 | biostudies-arrayexpress
ProteomicsNovel role of LRP1 in the regulation of smooth muscle contractile function by regulating cytoskeletal dynamics and Ca2+ signaling.
This project contains the proteomics data for the manuscript "Novel role of LRP1 in the regulation of smooth muscle contractile function by regulating cytoskeletal dynamics and Ca2+ signaling." by Au et al.
ORGANISM(S): Mus musculus (Mouse) 
2018-10-22 | PXD007544 | Pride
Dda Lrp1 Proteomics Aorta Shotgun Cardiovascular Lc-msms 
UnknownAbscisic Acid and Its Receptors LANCL1 and LANCL2 Control Cardiomyocyte Mitochondrial Function, Expression of Contractile, Cytoskeletal and Ion Channel Proteins and Cell Proliferation via ERRα.
Not available
S-EPMC10526111 | biostudies-literature
ProteomicsSeptin 7 Interacts With Numb To Preserve Sarcomere Structural Organization And Muscle Contractile Function
Here, we investigated mechanisms by which aging-related reductions of the levels of Numb in skeletal muscle fibers contribute to loss of muscle strength and power, two critical features of sarcopenia. Numb is an adaptor protein best known for its critical roles in development including asymmetric ce...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-04-28 | MSV000089327 | MassIVE
UnknownTwo Caenorhabditis elegans calponin-related proteins have overlapping functions that maintain cytoskeletal integrity and are essential for reproduction.
Not available
S-EPMC7443509 | biostudies-literature
UnknownSeptins, a cytoskeletal protein family, with emerging role in striated muscle.
Not available
S-EPMC8332580 | biostudies-literature
ProteomicsVinculin-network mediated cytoskeletal remodeling regulates contractile function in the aging heart - Monkey data
The human heart is capable of functioning for decades despite minimal cell turnover or regeneration, suggesting that molecular alterations help sustain heart function with age. However, identification of compensatory remodeling events in the aging heart remains elusive. Here we present the proteomes...
ORGANISM(S): Macaca mulatta (Rhesus macaque) 
2018-10-19 | PXD001842 | Pride
Proteomics Rattus norvegicus Mass spectrometry Cytoskeleton Macacca mulatta Biomarkers Stiffness Drosophila melanogaster 
ProteomicsVinculin-network mediated cytoskeletal remodeling regulates contractile function in the aging heart - Rat Data
The human heart is capable of functioning for decades despite minimal cell turnover or regeneration, suggesting that molecular alterations help sustain heart function with age. However, identification of compensatory remodeling events in the aging heart remains elusive. Here we present the proteomes...
ORGANISM(S): Rattus norvegicus (Rat) 
2016-04-15 | PXD001839 | Pride
Proteomics Rattus norvegicus Mass spectrometry Cytoskeleton Macacca mulatta Biomarkers Stiffness Drosophila melanogaster 
UnknownCytoskeletal remodeling slows cross-bridge cycling and ATP hydrolysis rates in airway smooth muscle.
Not available
S-EPMC7435030 | biostudies-literature
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