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ProteomicsIn vivo Mapping of the Mouse Galnt3-specific O-Glycoproteome
The polypeptide:N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes initiates O-linked glycosylation by catalyzing the addition of the first GalNAc sugar to serine or threonine on proteins destined to be membrane-bound or secreted. Defects in individual isoforms of the GalNAc-T family can...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD047517 | Pride
Galnac-t  galnt  glycopeptides  glycosyltransferase  hyperphosphatemic familial tumoral calcinosis (hftc)  o-galnac  o-glycosylation Mass spectrometry 
ProteomicsiTRAQ analysis of K562 cell line
K562 cells untreated (S) and treated (S+IM) with Imatinib as well as sensitive (S+IM) and resistant (R) to imatinib were subjected to labelled quantification by iTRAQ to identify Bcr-Abl downstream signaling components and proteins modulated in resistance respectively
ORGANISM(S): Homo sapiens (Human) 
2021-10-05 | PXD025173 | Pride
K562 Itraq 
ProteomicsGefitinib results in robust host-directed immunity against Salmonella infection through proteo-metabolomic reprogramming.
The rise of antibiotic-resistant strains of Salmonella has demand the development of alternative therapeutic strategies. Recent studies have shown that targeting host factors may provide an alternative approach for the treatment of intracellular pathogens. Host-directed therapy (HDT) modulates host ...
ORGANISM(S): Homo sapiens (Human) 
2021-03-26 | PXD024771 | Pride
Salmonella Proteo-metabolomic Dia Swath-ms Thp-1 
UnknownA molecular switch for neuroprotective astrocyte reactivity.
Not available
S-EPMC11384621 | biostudies-literature
UnknownHeat stress tolerance indices for identification of the heat tolerant wheat genotypes.
Not available
S-EPMC10322891 | biostudies-literature
ProteomicsFederated deep learning enables cancer subtyping by proteomics
Artificial intelligence (AI) applications in biomedical settings face challenges such as data privacy and regulatory compliance. Federated Deep Learning (FDL) effectively addresses these issues. We developed ProCanFDL, where local models were trained on simulated sites using proteomic data drawn fro...
ORGANISM(S): Homo sapiens (Human) 
2025-05-29 | PXD056810 | Pride
Procanfdl Pan-cancer Human Swath-ms Proteomics Federated deep learning 
UnknownStructural characterization and in-silico analysis of Momordica charantia 7S globulin for stability and ACE inhibition.
Not available
S-EPMC6981215 | biostudies-literature
ProteomicsSSSMuG: Same Sample Sequential Multi-Glycomics
The mammalian glycome is structurally complex and diverse, composed of many glycan classes such as N- and O-linked glycans, glycosaminoglycans (GAGs), glycosphingolipids (GSLs) and other distinct glycan features such as polysialic acids (PolySia), sulfation and proteoglycan attachment stubs. Various...
ORGANISM(S): Mus musculus (Mouse) 
2024-02-13 | PXD046012 | Pride
Multi-glycomics Glycome Proteomics Glycoconjugate Multi-omics Brain 
UnknownUrease Inhibitory Kinetic Studies of Various Extracts and Pure Compounds from Cinnamomum Genus.
Not available
S-EPMC8270325 | biostudies-literature
UnknownUnderstanding knowledge and media influence on people with hepatitis B in Senegal: a mixed-methods study.
Not available
S-EPMC11934370 | biostudies-literature
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