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ProteomicsSSSMuG: Same Sample Sequential Multi-Glycomics
The mammalian glycome is structurally complex and diverse, composed of many glycan classes such as N- and O-linked glycans, glycosaminoglycans (GAGs), glycosphingolipids (GSLs) and other distinct glycan features such as polysialic acids (PolySia), sulfation and proteoglycan attachment stubs. Various...
ORGANISM(S): Mus musculus (Mouse) 
2024-02-13 | PXD046012 | Pride
Multi-glycomics Glycome Proteomics Glycoconjugate Multi-omics Brain 
ProteomicsLong term intrathecal administration of morphine vs baclofen: differences in CSF identified using multi-glycomics
CSF samples from patients that had long-term (>2years), intrathecal morphine or baclofen administered via an indwelling pump, and we performed proteomics and multi-glycomics via sequential release of polysialic acids, glycosaminoglycans, N-glycans and O-glycans from the same sample material.
ORGANISM(S): Homo sapiens (Human) 
2023-10-10 | PXD023111 | Pride
Multi-glycomics Csf Intrathecal Morphine Long-term 
MetabolomicsA Multi-Omic View of Host-Pathogen-Commensal Interplay in Salmonella-Mediated Intestinal Infection
The potential for commensal microorganisms indigenous to a host (the microbiome or microbiota) to alter infection outcome by influencing host-pathogen interplay is largely unknown. We used a multi-omics systems approach, incorporating proteomics, metabolomics, glycomics, and metagenomics, to explore...
2014-06-24 | MTBLS96 | MetaboLights
ProteomicsReduction of charged glycoconjugates in TANGO2 KO mouse brain
The transport and Golgi organization 2 (TANGO2) gene has been identified to cause a rare recessive genetic disorder known as TANGO2-deficiency disorder (TDD). TDD is a multisystemic disorder that can affect different organs including the brain, heart, and muscles, presenting as recurrent metabolic c...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-10 | PXD068411 | Pride
Tango2 Mouse Glycomics Dda 
UnknownComparison of analytical methods for profiling N- and O-linked glycans from cultured cell lines : HUPO Human Disease Glycomics/Proteome Initiative multi-institutional study.
Not available
S-EPMC4848167 | biostudies-literature
ProteomicsComprehensive glycoprofiling of oral tumours associates N-glycosylation with lymph node metastasis and patient survival
While altered protein glycosylation is regarded a trait of oral squamous cell carcinoma (OSCC), its heterogeneous glycoproteome and dynamics with disease progression remain unmapped. Employing an integrated multi-omics approach comprising unbiased and quantitative glycomics and glycoproteomics on re...
ORGANISM(S): Homo sapiens (Human) 
2023-06-08 | PXD037134 | Pride
Glycomics Lymph node metastasis Glycoproteomics Glycosylation Glycoproteome Oral cancer 
UnknownMulti-Omics Investigation into Acute Myocardial Infarction: An Integrative Method Revealing Interconnections amongst the Metabolome, Lipidome, Glycome, and Metallome.
Not available
S-EPMC9693522 | biostudies-literature
UnknownGlycoproteome remodeling in MLL-rearranged B-cell precursor acute lymphoblastic leukemia.
Not available
S-EPMC8490503 | biostudies-literature
UnknownProfound N-glycan remodelling accompanies MHC-II immunopeptide presentation.
Not available
S-EPMC10663315 | biostudies-literature
UnknownDecoding the mechanism of hypertension through multiomics profiling.
Not available
S-EPMC10063442 | biostudies-literature
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