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ProteomicsCOMPARATIVE PROTEOMICS ANALYSIS OF THE IRIDOCORNEAL REGION OF DBA/2J AND DBA/2J-Gpnmb+/SjJ MICE
In this study, we performed a comparative proteomics analysis of the iridocorneal region in DBA/2J and Gpnmb+ mice to gain deeper insight into the molecular mechanisms underlying IOP elevation following iris pigment dispersion/
ORGANISM(S): Mus musculus (Mouse) 
2026-02-09 | PXD064786 | Pride
Gpnmb Proteomics Glaucoma Ocular hypertension Outflow pathway Dba/2j Iridocorneal region 
TranscriptomicsTranscription profiling of mouse model of glaucoma retinal RNA from DBA/2J mice at 3 months before disease onset, and at 8 months, after IOP elevation
Purpose: The DBA/2J mouse is a model for secondary angle-closure glaucoma due to iris atrophy and pigment dispersion, which ultimately leads to increased intraocular pressure (IOP). We sought to correlate changes in retinal gene expression with glaucoma-like pathology by performing microarray analys...
ORGANISM(S): Mus musculus 
2007-12-15 | E-GEOD-3554 | biostudies-arrayexpress
GenomicsMus musculus strain:DBA/2J
Genome sequencing of the DBA/2J strain of mouse
PRJNA33589 | ENA
TranscriptomicsGene expression in LSK cells of C57B/L6, DBA/2J, B.D(Chr5), & D.B(Chr5) mice
These mouse strains differ in absolute numbers of hematopoietic stem cells but differ genetically only at the Chr 5 congenic locus. We used microarray analysis to identify candidate regulators of hematopoietic stem cells based on differential gene expression patterns. Triplicate RNA samples, except ...
ORGANISM(S): Mus musculus 
2010-05-21 | E-GEOD-21896 | biostudies-arrayexpress
GenomicsMus musculus strain:DBA/2J & C57BL/6J
Structural variation study of DBA/2J and C57BL/6J mice
PRJNA41995 | ENA
GenomicsCOMPARATIVE RNAseq ANALYSIS OF THE IRIDOCORNEAL REGION OF DBA/2J AND DBA/2J-Gpnmb+/SjJ MICE
COMPARATIVE RNAseq ANALYSIS OF THE IRIDOCORNEAL REGION OF DBA/2J AND DBA/2J-Gpnmb+/SjJ MICE
PRJNA1273129 | ENA
TranscriptomicsTranscription profiling of mouse age-related hearing loss cochlea in DBA/2J
Age-related hearing loss (AHL) is the progressive loss of auditory function with aging. The DBA/2J (DBA) mice have been used as a model of AHL and undergoes progressive, age-related hearing loss by 12 weeks of age. Here we analyzed cochlear gene expression of 7-week-old and 36-week-old DBA mice usin...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-6045 | biostudies-arrayexpress
TranscriptomicsDifferential response of C57BL/6J mouse and DBA/2J mouse to optic nerve crush
Retinal ganglion cell (RGC) death is the final consequence of many blinding diseases, where there is considerable variation in the time course and severity of RGC loss. Indeed, this process appears to be influenced by a wide variety of genetic and environmental factors. In this study we explored the...
ORGANISM(S): Mus musculus 
2010-08-19 | E-GEOD-17117 | biostudies-arrayexpress
UnknownAqueous humor phospholipids of DBA/2J and DBA/2J-Gpnmb(+)/SjJ mice.
Not available
S-EPMC4430412 | biostudies-literature
TranscriptomicsNovel aspects of the transcriptional stress response in the paraventricular nucleus of the mouse strains DBA/2J and C57BL/6J
The pivotal role of stress in the precipitation of psychiatric diseases is generally accepted. To further elucidate the underlying molecular mechanisms, gene networks and signalling cascades, we investigated the impact of an acute stressor, forced swimming, on the gene expression profile in the hypo...
ORGANISM(S): Mus musculus 
2010-10-20 | E-GEOD-20877 | biostudies-arrayexpress
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