Sort   by:  
 Page size 
ProteomicsSARS-CoV-2 Infection Impacts Glutamate/Glutamine Metabolism in Syrian Hamster Central Nervous System
Coronaviruses belong to a well-known family of enveloped RNA viruses and the causative agent of the common cold. Although the seasonal coronaviruses do not pose a threat to human life, three members of this family, i.e., SARS-CoV, MERS-CoV and recently, SARS-CoV2, may cause severe acute respiratory ...
ORGANISM(S): Mesocricetus auratus (Golden hamster) 
2022-09-28 | PXD029426 | Pride
Sars-cov2 Proteomics Glutamine Neuropathology Covid-19 
ProteomicsSARS-CoV-2 induced glycolysis is essential for monocytes inflammatory response
We have analyzed through shotgun proteomics approach Macrophages and Monocytes infected by the virus Sars-Cov 2, performing a qualitative and quantitative analysis.
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD019157 | Pride
Covid-19 Sars-cov2 Proteomics 
ProteomicsCOVID-19 PATIENTS WITH NEUROLOGICAL SYMPTOMS PRESENT BROAD CENTRAL NERVOUS SYSTEM MOLECULAR AND STRUCTURAL ALTERATIONS ASSOCIATED WITH SYSTEMIC INFLAMMATION AND DISEASE SEVERITY
Background. COVID-19-induced neurological disease is a growing concern. Here we provide a comprehensive clinical, molecular, and neuroimaging investigation of patients presenting neurological symptoms to investigate underlying processes. Methods. We performed a detailed systematized clinical, labor...
ORGANISM(S): Homo sapiens (Human) 
2024-08-09 | PXD033979 | Pride
Cerebrospinal fluid Csf Inflammation Prorteomics Covid-19 
ProteomicsSARS-CoV-2 infects brain astrocytes of COVID-19 patients and impairs neuronal viability
COVID-19 patients may exhibit neuropsychiatric and neurological symptoms. We found that anxiety and cognitive impairment are manifested by 28-56% of SARS-CoV-2-infected individuals with mild respiratory symptoms and are associated with altered cerebral cortical thickness. Using an independent cohort...
ORGANISM(S): Homo sapiens (Human) 
2022-09-01 | PXD023781 | Pride
Covid-19 Astrocytes Proteomics Sars-cov2 
ProteomicsSARS-CoV-2 infects adipocytes in a fat depot- and viral strain-dependent manner
Visceral adiposity is a risk factor for severe COVID-19 and a link between adipose tissue infection and disease progression has been proposed. Here we demonstrate that SARS-CoV-2 undergoes productive infection in adipocytes, although the degree of infection and the cellular response depend on the an...
ORGANISM(S): Homo sapiens (Human) 
2024-02-29 | PXD030910 | Pride
Visceral adipocytes Inflammatory response Subcutaneous adipocytes Adipocytes Sars-cov-2 infection 
TranscriptomicsComprehensive identification of miRNAs involved in eucalypt xylogenesis
Identification of miRNAs in the xylem of Eucalyptus globublus. Samples were taken from different seasons and at different time points from the tension and opposition wood of bent branches.
ORGANISM(S): Eucalyptus globulus 
2015-09-06 | E-MTAB-2997 | biostudies-arrayexpress
UnknownIntegrative proteomics and pharmacogenomics analysis of methylphenidate treatment response.
Not available
S-EPMC6861257 | biostudies-literature
UnknownHOXA9 transcriptomic analysis in GBM cell lines (U87MG, U251 and primary GBML18) and in immortalized human astrocytes (hTERT/E6/E7)
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-56517 | biostudies-other
TranscriptomicsHigh-throughput sequencing of small RNA transcriptomes and DNA microarrays reveal critical biological features targeted by microRNAs in cell models used for squamous cell cancer research
Background The implication of post-transcriptional regulation by microRNAs in molecular mechanisms underlying cancer disease is well documented. However, their interference at the cellular level is not fully explored. Functional in vitro studies are fundamental for the comprehension of their role; n...
ORGANISM(S): Homo sapiens 
2013-12-30 | E-GEOD-41436 | biostudies-arrayexpress
UnknownShaping current European mitochondrial haplogroup frequency in response to infection: the case of SARS-CoV-2 severity.
Not available
S-EPMC11718132 | biostudies-literature
Sort   by:  
 Page size