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ProteomicsHuman CSF peptidomics of gamma secretase inhibition
Fifteen human healthy volunteers, divided into three groups, received a single dose of placebo or either 140 mg or 280 mg of the ?-secretase inhibitor semagacestat (LY450139). Endogenous peptides in CSF, sampled prior to administration of the drug and at six subsequent time points, were analyzed by ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080870 | MassIVE
ProteomicsPhosphate-binding pocket on cyclin B governs CDK substrate phosphorylation and mitotic timing
Cell cycle progression is governed by complexes of the cyclin-dependent kinases (CDKs) and their regulatory subunits cyclin and Cks1. CDKs phosphorylate hundreds of substrates, often at multiple sites. Multisite phosphorylation depends on Cks1, which binds initial priming phosphorylation sites to pr...
ORGANISM(S): Saccharomyces cerevisiae Saccharomyces cerevisiae (Baker's yeast) 
2025-05-19 | PXD062428 | Pride
Human Lfq Cdk Phosphoproteomics Yeast Lcms 
UnknownHemolysis During Pediatric Extracorporeal Membrane Oxygenation: Associations With Circuitry, Complications, and Mortality.
Not available
S-EPMC6218309 | biostudies-literature
UnknownAcquired infection during neonatal and pediatric extracorporeal membrane oxygenation.
Not available
S-EPMC6103806 | biostudies-literature
UnknownHyperoxia and Hypocapnia During Pediatric Extracorporeal Membrane Oxygenation: Associations With Complications, Mortality, and Functional Status Among Survivors.
Not available
S-EPMC5834382 | biostudies-literature
UnknownRisk Factors for Mortality in Refractory Pediatric Septic Shock Supported with Extracorporeal Life Support.
Not available
S-EPMC7773130 | biostudies-literature
UnknownA Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci.
Not available
S-EPMC5524541 | biostudies-literature
UnknownA Core Outcome Measurement Set for Pediatric Critical Care.
Not available
S-EPMC9633391 | biostudies-literature
UnknownVisual Acuity and Ophthalmic Outcomes 5 Years After Cataract Surgery Among Children Younger Than 13 Years.
Not available
S-EPMC8832311 | biostudies-literature
UnknownBiallelic CRELD1 variants cause a multisystem syndrome, including neurodevelopmental phenotypes, cardiac dysrhythmias, and frequent infections.
Not available
S-EPMC10932913 | biostudies-literature
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