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ProteomicsThe ribotoxic stress response drives UV-mediated cell death.
Supporting raw MS data for paper (doi: 10.1016/j.cell.2024.05.018) by Sinha N.K. et al, titled "The ribotoxic stress response drives UV-mediated cell death". Index of MS files and labels Table S1 - HaCaT Timecourse. 1-1 - Proteome (AO3604-3627 | Unimod:35; 2016; 4 | 126 -UT_01; 127n - UT_02; 12...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-07-25 | MSV000092521 | MassIVE
TranscriptomicsWidespread regulated alternative splicing of single codons accelerates proteome evolution
Thousands of human genes contain introns ending in NAGNAG motifs (N any nucleotide), where both NAGs can function as 3' splice sites, yielding isoforms differing by inclusion/exclusion of just three bases. However, the functional importance of NAGNAG alternative splicing is highly controversial. Usi...
ORGANISM(S): Homo sapiens 
2012-01-05 | E-GEOD-30017 | biostudies-arrayexpress
TranscriptomicsA proteomic view on the cell biology of Staphylococcus aureus proteome
The genome sequence is the “blue-print of life”, but proteomics is required to relate this blue-print of life to the actual physiology of living cells. Because of their low complexity – only about 2.000 proteins make a Staphylococcus aureus cell viable – bacteria are excellent model systems to ident...
ORGANISM(S): Staphylococcus aureus 
2009-11-11 | E-GEOD-15060 | biostudies-arrayexpress
UnknownDiffusive Dynamics of Bacterial Proteome as a Proxy of Cell Death.
Not available
S-EPMC9881203 | biostudies-literature
ProteomicsProteome analysis of pathogen-induced regulated cell death in maize
Regulated cell death (RCD) is crucial for plant development, as well as in decision-making in plant-pathogen interactions. Previous studies revealed components of the molecular network controlling RCD, including different proteases. However, the identity, the proteolytic network as well as molecular...
ORGANISM(S): Zea mays (Maize) 
2023-07-13 | PXD041377 | Pride
Zea mays Fumonisin b1 Dia Mass spectrometry Ms Fb1 Rcd Avrrxo1 Sa Salicylic acid 
TranscriptomicsEIF4E AND EIF4GI HAVE DISTINCT AND DIFFERENTIAL IMPRINTS ON MULTIPLE MYELOMA'S PROTEOME AND SIGNALING
Accumulating data indicate translation plays a role in cancer biology, particularly its rate limiting stage of initiation. Despite this evolving recognition, the function and importance of specific translation initiation factors is unresolved. The eukaryotic translation initiation complex eIF4F cons...
ORGANISM(S): Homo sapiens 
2015-10-29 | E-GEOD-62821 | biostudies-arrayexpress
UnknownPlatelet proteome reveals features of cell death, antiviral response and viral replication in covid-19.
Not available
S-EPMC9287722 | biostudies-literature
ProteomicsN-terminome analysis of pathogen-induced cell death in maize
Regulated cell death (RCD) is crucial for plant development, as well as in decision-making in plant-pathogen interactions. Previous studies revealed components of the molecular network controlling RCD, including different proteases. However, the identity, the proteolytic network as well as molecular...
ORGANISM(S): Zea mays (Maize) 
2023-07-13 | PXD041656 | Pride
Zea mays Regulated cell death Fb1 Rcd Plants Avrrxo1 Hunter 
TranscriptomicsWhy does HAMLET preferentially kill tumor cells? p38-dependent death in tumor but up-regulation of innate immunity in healthy, differentiated cells
HAMLET triggers a p38- and ER stress-dependent death response in carcinoma cells. Transcriptome and proteome analysis detected an increase in p38 expression and phosphorylation exclusively in carcinoma cells and p38 inhibitors delayed the death response to HAMLET in carcinoma and lymphoma cells. ER...
ORGANISM(S): Homo sapiens 
2010-08-24 | E-GEOD-23772 | biostudies-arrayexpress
ProteomicsPLATELET PROTEOME REVEALS FEATURES OF CELL DEATH, ANTIVIRAL RESPONSE AND VIRAL REPLICATION IN COVID-19.
This article provides the first proteomic analysis of platelets from COVID-19 patients. Our dataset shows that platelets are reprogrammed during severe COVID-19 and respond with the activation of type I interferon and cell death pathways, indicating platelet participation in the antiviral response. ...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD031251 | Pride
Proteome Platelet Covid-19 
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