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MetabolomicsUnveiling superior phenol detoxification and degradation ability in Candida tropicalis SHC-03: A comparative study with Saccharomyces cerevisiae BY4742

This study examined the phenol degradation capabilities and oxidative stress responses of Candida tropicalis SHC-03, demonstrating its metabolic superiority and resilience compared to Saccharomyces cerevisiae BY4742 in a culture medium with phenol as the sole carbon source. Through comparative gr...

2024-10-04 | MTBLS10757 | MetaboLights
MetabolomicsMechanisms of poly(butylene adipate-co-terephthalate) microplastic degradation in agricultural soil: Insights from the soybean rhizosphere

The increasing application of biodegradable mulch films in agriculture has raised concerns regarding the potential persistence of biodegradable microplastics (BMPs) in soil and their subsequent ecological impacts. Although these materials are designed to mineralize, their actual rates of breakdow...

2026-01-07 | MTBLS12524 | MetaboLights
ProteomicsChanges in Protein Turn-over Rates Regulate Tryptophan and Glucosinolate Biosynthesis, IAA Transport and Photosynthesis in Arabidopsis Growth and Defense Transitions
Changes in protein synthesis and degradation rates, transcript, protein and phytohormone abundance of 99 targets using qPCR and LC-MS parallel reaction monitoring (PRM) were measured in the transitions between optimal growth conditions (homeostasis), fully induced pattern triggered immunity (PTI) an...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-10-13 | PXD041215 | Pride
Translational regulation Photosynthesis Protein degradation rates Pti Glucosinolates Myc2 Phytohormone Proteomics Protein synthesis rates Auxin Pin proteins 
TranscriptomicsRNA degradation in proliferating and differentiated C2C12 muscle precursor cells analyzed on Affymetrix exon arrays
Steady-state RNA levels are a result of RNA synthesis and degradation. The importance of transcription-factor mediated induction or repression of mRNA synthesis is well established, but the role and mechanisms of RNA degradation are less well understood. We globally evaluated the RNA decay rates in ...
ORGANISM(S): Mus musculus 
2010-09-22 | E-GEOD-14387 | biostudies-arrayexpress
TranscriptomicsGlobal analysis of mRNA degradation reveals Xrn1-dependent buffering of transcript levels
The rates of mRNA synthesis and degradation determine cellular mRNA levels and can be monitored by comparative Dynamic Transcriptome Analysis (cDTA) that uses non-perturbing metabolic RNA labeling. Here we present cDTA data for 46 yeast strains lacking genes involved in mRNA degradation and metaboli...
ORGANISM(S): Schizosaccharomyces pombe 
2013-10-18 | E-MTAB-1525 | biostudies-arrayexpress
GenomicsscDUAL-seq Simultaneously Measures RNA Synthesis and Degradation Rates in Single Cells
scDUAL-seq Simultaneously Measures RNA Synthesis and Degradation Rates in Single Cells
PRJNA1209856 | ENA
TranscriptomicsMeasurement of temperature affects on Arabidopsis transcription and decay rates
The goal of this study is to measure Arabidopsis mRNA transcription and mRNA decay rates genome wide at two temperatures, and thus to calculate the temperature coefficient of both processes. Sensing and response to ambient temperature is important for controlling growth and development of many organ...
ORGANISM(S): Arabidopsis thaliana 
2013-12-07 | E-GEOD-53071 | biostudies-arrayexpress
GenomicsThe taxon-specific degradation of soil extracellular 16S rRNA genes: rates, influential factors, and implications
The taxon-specific degradation of soil extracellular 16S rRNA genes: rates, influential factors, and implications Metagenome
PRJNA1141901 | ENA
ProteomicsGlobal analysis of protein degradation rates during prion infection
Prion diseases are rare, neurological disorders caused by the misfolding of the cellular prion protein (PrPC). The misfolded conformers aggregate into cytotoxic fibrils (PrPSc) that facilitate the conversion of additional prion proteins into their misfolded form. Intracellular PrPSc aggregates prima...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-08 | PXD014577 | Pride
N2a Lysosome Cell culture Prion Rml 
TranscriptomicsRole of mRNA stability during bacterial adaptation
Bacterial adaptation involves extensive cellular reorganization. In particular, growth rate adjustments are associated with substantial modifications of gene expression and mRNA abundance. In this work we aimed to assess the role of mRNA degradation during such variations. A genome-wide transcript...
ORGANISM(S): Lactococcus lactis 
2014-06-16 | E-GEOD-43875 | biostudies-arrayexpress
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