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TranscriptomicsExposure of Deinococcus Radiodurans to 1126 Days in low Earth orbit: Molecular Patterns of Recovery after Tanpopo space Mission
Background: The International Space Station is an orbiting laboratory for microbial research in space, where microorganisms can be exposed to multiple extremes. Dehydrated cell clusters of extremophilic bacterium Deinococcus radiodurans have survived 3-year exposure outside the International Space S...
ORGANISM(S): Deinococcus radiodurans 
2025-02-27 | E-MTAB-13969 | biostudies-arrayexpress
TranscriptomicsTranscriptional Analysis of Deinococcus radiodurans for Novel sRNAs expression that are Differentially Expressed under Ionizing Radiation
In this study, we identified potential sRNA candidates in D. radiodurans by a whole transcriptome deep sequencing analysis, and confirm the expression of 31 sRNAs in D. radiodurans with Northern blotting analysis and RT-PCR. A total of 8 confirmed sRNAs showed differential expression during recover...
ORGANISM(S): Deinococcus radiodurans R1 
2015-01-22 | E-GEOD-64952 | biostudies-arrayexpress
ProteomicsA small RNA regulates pprM, a modulator of pleiotropic proteins promoting DNA repair, in Deinococcus radiodurans under ionizing radiation
This study tracks the proteome during recovery from 10 kGy acute ionizing radiation (IR) in Deinococcus radiodurans R1 (WT). After 1 hour of recovery post-IR exposure, we observed 37 proteins significantly differentially expressed, including several within the Radiation and Dessication Response (RDR...
ORGANISM(S): Deinococcus radiodurans R1 
2021-06-25 | PXD026633 | Pride
Deinococcus Shotgun proteomics Ir Srna Ionizing radiation Deinococcus radiodurans Timecourse 
ProteomicsMolecular repertoire of Deinococcus radiodurans after 1 year of exposure outside the International Space Station within the Tanpopo mission
Abstract Background The extraordinarily resistant bacterium Deinococcus radiodurans withstands harsh environmental conditions present in outer space. Deinococcus radiodurans was exposed for one year outside the International Space Station within Tanpopo orbital mission to investigate microbial surv...
ORGANISM(S): Deinococcus radiodurans R1 
2021-09-09 | PXD020047 | Pride
Molecular stress response Proteomics Metabolomics Deinococcus radiodurans Low earth orbit Transcriptomics 
TranscriptomicsDeinococcus radiodurans R1 Cells: Control vs. bphPR deletion mutant
Transcriptional profiling of Deinococcus radiodurans comparing control wild type cells with bphPR deletion mutant Two-condition experiment, R1 vs. bphPR deletion cell. Biological replicates: 3 control replicates, 3 bphPR deletion mutant replicates.
ORGANISM(S): Deinococcus radiodurans R1 
2014-07-07 | E-GEOD-59135 | biostudies-arrayexpress
ProteomicsIdentification of PNPase and RhlB binding proteins in Deinococcus radiodurans
8-oxo-7,8-dihydroguanine (8-oxoG) is a common RNA oxidation that has been implicated in carcinogenesis, neurodegeneration, and aging. Some? Many? RNA-binding proteins have shown binding preference for 8-oxoG modified RNA; such binding? can protect cells from oxidative stress. To date, the presence o...
ORGANISM(S): Deinococcus radiodurans ATCC 13939 
2022-07-09 | PXD028866 | Pride
8-oxo-7 8-dihydroguanine  rna oxidation  rna binding proteins  pnpase  rhlb  oxidative stress  deinococcus radiodurans  rna degradation 
ProteomicsIdentification of 8-oxoG binding proteins in Deinococcus radiodurans
8-oxo-7,8-dihydroguanine (8-oxoG) is a common RNA oxidation that has been implicated in carcinogenesis, neurodegeneration, and aging. Some? Many? RNA-binding proteins have shown binding preference for 8-oxoG modified RNA; such binding? can protect cells from oxidative stress. To date, the presence o...
ORGANISM(S): Deinococcus radiodurans ATCC 13939 
2022-07-10 | PXD028861 | Pride
8-oxo-7 8-dihydroguanine  rna oxidation  rna binding proteins  pnpase  rhlb  oxidative stress  deinococcus radiodurans  rna degradation 
ProteomicsSuccinylome analysis reveals the involvement of lysine succinylation in extreme resistance of Deinococcus radiodurans
Increasing evidences showing that succinylation of lysine residue mainly regulates enzymes involved in the carbon metabolism pathway, both in prokaryotic and eukaryotic cells. Deinococcus radiodurans is one of the most radioresistant organisms on earth, which is famous for its robust resistance. A m...
ORGANISM(S): Deinococcus radiodurans 
2021-04-26 | PXD012149 | Pride
Succinylome  succinylation  dna repair  nucleic acid binding  posttranslational modification 
ProteomicsThe identification and analysis of sORF and SEPs in Deinococcus radiodurans
The identification and analysis of sORF and SEPs in Deinococcus radiodurans
ORGANISM(S): Deinococcus Radiodurans R1 
2022-09-23 | PXD033880 |
ProteomicsIdentification of proteins in the interactomes of 4 DNA-repair proteins of Deinococcus radiodurans
Project includes identification of the interacting partners of the four important DNA-repair proteins (DdrA, DdrB, RecA, Ssb) of the extremophile D. radiodurans. The interacting proteins were crosslinked with DSP, immunoprecipitated using antibodies against the four DNA repair proteins, followed by...
ORGANISM(S): Deinococcus radiodurans R1 
2021-05-07 | PXD021822 | Pride
Deinococcus radiodurans dna damage repair 
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