Sort   by:  
 Page size 
TranscriptomicsGene expression changes upon knockdown of DEK in the U937 cell line
Gene expression profiling of U937 cells upon knockdown of the DEK oncogene by two different shRNAs (shDEK14 and shDEK17). The DEK oncogene was knocked down by shRNA to study the changes in gene expression.
ORGANISM(S): Homo sapiens 
2014-09-26 | E-GEOD-60732 | biostudies-arrayexpress
GenomicsGenome-wide mapping of DEK binding in the U937 cell line
We find that the DEK oncoprotein preferentially binds close to the transcription start sites of highly and ubiquitously expressed genes. Sequencing of DNA precipitated by an antibofy against the DEK oncoprotein (ChIP-seq).
ORGANISM(S): Homo sapiens 
2014-09-26 | E-GEOD-60692 | biostudies-arrayexpress
TranscriptomicsIdentifying DEK-dependent transcriptional signatures in HPV+ and HPV- head and neck squamous cell carcinoma (HNSCC)
We report the first RNA-Seq experiments profiling the effects of DEK loss in HNSCC. Our data also incorporates HPV+ and HPV- tumors to idenfity HPV-dependent and -independent gene signatures. RNA-Seq of DEK-dependent gene signatures in HNSCC cell lines
ORGANISM(S): Homo sapiens 
2016-02-05 | E-GEOD-70462 | biostudies-arrayexpress
ProteomicsDEK/NUP214 SILAC interactormics analysis
Among most of leukemogenic fusion proteins the aberrant localization that the translocation partners are forced in when compared to their wt counterparts contributes to leukemogenesis most likely by a sequester of interaction partners. The aim was to disclose the role of localization of DEK/NUP214...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD031885 | Pride
Silac Dek/nup214 Interactome 
ProteomicsProteomic discovery of DEK and NUMA1 as new players in UV-induced DNA damage repair mechanisms
Ultraviolet (UV)-induced DNA lesions threaten genomic stability and are associated with skin carcinogenesis. These lesions are primarily repaired by the nucleotide excision repair (NER) pathway. However, alternative repair mechanisms and regulators are emerging as critical contributors to managing U...
ORGANISM(S): Homo sapiens (Human) 
2025-12-01 | PXD061212 | Pride
Uv Uv Dek Numa1 Dna damage 
GenomicsTranscriptional Profiling of Lineage Depleted Dek-KO Murine Bone Marrow Treated with Exogenous DEK
Transcriptional Profiling of Lineage Depleted Dek-KO Murine Bone Marrow Treated with Exogenous DEK
PRJNA523588 | ENA
ProteomicsCK2-mediated DEK Phosphorylation Drives PBX3 Overexpression: A Core Event in Hematopoietic Stem Cell-to-Leukemia Stem Cell Transformation
1. LSCs from MLL-AF9-driven DekTg-fl, Tie2-Cre AML mice were sorted, followed by further proteomic assay. 2. To illustrate DEK-interacting proteins, we performed anti-Flag co-immunoprecipitation (co-IP) followed by mass spectrometry using MLL-AF9-driven LSCs to characterize protein interactomes of D...
ORGANISM(S): Mus musculus (Mouse) 
2026-07-06 | PXD068965 | Pride
Pbx3 Dek Leukemia stem cells 
GenomicsThe functional study of DEK in 786-O cells [ChIP]
The functional study of DEK in 786-O cells [ChIP]
PRJNA1017374 | ENA
GenomicsThe functional study of DEK in 786-O cells [ATAC]
The functional study of DEK in 786-O cells [ATAC]
PRJNA1017373 | ENA
GenomicsThe functional study of DEK in 786-O cells [RNA]
The functional study of DEK in 786-O cells [RNA]
PRJNA1017375 | ENA
Sort   by:  
 Page size