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This dataset assesses structural changes occurring in human, heme-bound HRI upon association with S-DELE1. To this end, human HRI and S-DELE1 were expressed EIF2alpha phosphorylation-resistent cells supplemented with hemin. HRI was affinity purified, crosslinked with DSS, and structural changes in H...
ORGANISM(S): Homo sapiens (Human) 
2026-05-07 | PXD063587 | Pride
This dataset assesses the effects of S-DELE1 association on the auto-phosphorylation of human, heme-bound HRI. Human HRI and DELE1 were expressed in EIF2alpha-phospho-resistant cells supplemented with hemin. HRI was affinity purified, the elution subjected to denaturing gel electrophoresis, and HRI...
ORGANISM(S): Homo sapiens (Human) 
2026-06-09 | PXD062916 | Pride
Expression data from P140 C10 S59L Dele1 mouse hearts
Expression data from P28 C10 G58R Dele1 mouse hearts
Expression data from P28 C10 G58R Dele1 mouse gastrocnemius muscles.
Expression data from P56 Ckmm-cre Tfam Dele1 mouse hearts
DELE1 mitochondrial integrated stress response to CHCHD10 G58R protein misfolding in striated muscle [RNA-seq]
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