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ProteomicsRobust, reproducible, and economical phosphopeptide enrichment using calcium titanate.
We compare different preparations of TiO2 for phosphopeptide enrichment and demonstrate the efficacy of a method using CaTiO3
ORGANISM(S): Homo sapiens (Human) 
2019-01-02 | PXD011145 | Pride
Phosphoproteomics Enrichment Phosphopeptide 
ProteomicsQuantitative Proteomic Analysis Reveals Posttranslational Responses to Aneuploidy in Yeast
Aneuploidy causes severe developmental defects and is a near universal feature of tumor cells. Despite its profound effects, the cellular processes affected by aneuploidy are not well characterized. Here, we examined the consequences of aneuploidy on the proteome of aneuploid budding yeast strains. ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2014-08-14 | PXD001019 | Pride
Tmt Silac Aneuploidy Saccharomyces cerevisiae 
ProteomicsKLF4 binding is involved in the organization and regulation of 3D enhancer networks during acquisition and maintenance of pluripotency.
Cell fate transitions are accompanied by global transcriptional, epigenetic and topological changes driven by transcription factors (TFs), as is strikingly exemplified by reprogramming somatic cells to pluripotent stem cells (PSCs) via expression of OCT4, KLF4, SOX2 and cMY...
ORGANISM(S): Mus musculus (Mouse) 
2019-09-03 | PXD014631 | Pride
Pluripotency Ipscs Stem cells Rime Chromatin 
ProteomicsCHD1_RIME - CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis
Crosslinked chromatin bound protein complexes were immunopurified, digested, and analyzed by mass spectrometry to identify and quantify proteins associate with the chromodomain helicase (Chd1).
ORGANISM(S): Homo sapiens (Human) 
2019-08-13 | PXD010468 | Pride
Prostate cancer Rime Chromatin 
ProteomicsConsequences of aneuploidy in human fibroblasts
To characterize aneuploidy driven phenotypes in human trisomies, we performed global transcriptome, proteome, and phenotypic analysis of primary human fibroblasts from individuals with Patau (trisomy 13), Edwards (trisomy 18), or Down syndromes.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-07-09 | MSV000085706 | MassIVE
ProteomicsA conserved signaling network monitors delivery of sphingolipids to the plasma membrane in budding yeast.
48 total runs: three biological replicates, 8 runs each, each run as technical duplicates
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
2017-04-13 | MSV000080919 | MassIVE
ProteomicsAge-induced methylmalonic acid accumulation promotes cancer aggressiveness and metastatic disease
TMT protein abundance profiling of human serum from 30 young and 30 older adults.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-02-18 | MSV000084974 | MassIVE
OtherQuantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast.
Data from ProteomeXchange, PXD ID: PXD001019. Experiment: Dis14, file: folder summary. Published as part of Elife. 2014 Jul 29:e03023 . From the Abstract: {{i}} Aneuploidy causes severe developmental defects and is a near universal feature of tumor cells. Despite its profound effects, the cellular ...
ORGANISM(S): Yeast 
GPM32320002303 | GPMDB
Resource Reanalysis 
TranscriptomicsIdentification of Aneuploidy-tolerating Mutations
Aneuploidy causes a proliferative disadvantage in all cells analyzed to date, yet this condition is associated with a disease characterized by unabated proliferative potential, cancer. The mechanisms that allow cancer cells to tolerate the adverse effects of aneuploidy are not known. To probe this q...
ORGANISM(S): Saccharomyces cerevisiae 
2010-02-24 | E-GEOD-20464 | biostudies-arrayexpress
ProteomicsS.cerevisiae - Whole organism, Immunodetection of tagged proteins, normalized data (Ghaemmaghami,nature,2003)
abundance based on normalized data, immunodetection of tagged proteins, Interaction consistency score: 6.5, Coverage: 58
ORGANISM(S): 4932 
2003-00-00 | 420765789 | PAXDB
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