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TranscriptomicsGene expression profiling of the effects of Cyclophosphamide on peripheral blood mononuclear cells
Certain anticancer drugs, particularly cyclophosphamide (CTX), were shown to enhance the antitumor efficacy of immunotherapy through different immunomodulatory mechanisms. A better understanding of the cellular and molecular basis of CTX-mediated immunomodulation is needed to improve the efficacy of...
ORGANISM(S): Homo sapiens 
2013-09-02 | E-GEOD-39324 | biostudies-arrayexpress
ProteomicsMagnetic resonance imaging and transcriptome-proteome integration analysis demonstrate improved disease-outcome in the cuprizone mouse model following AAV-mediated delivery of A Proliferation Inducing Ligand
A Proliferation Inducing Ligand (APRIL) is a member of the tumour necrosis factor (TNF) superfamily and has recently been shown to modulate pro-inflammatory astrocyte responses, as well as to ameliorate disease outcome in the experimental autoimmune encephalomyelitis mouse model for multiple scleros...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-10 | PXD056011 | Pride
Cuprizone Adeno-associated virus Neuroprotection Neuroinflammation Magnetic resonance imaging Transcriptomics Proteomics April 
ProteomicsStructural and functional analysis of the novel pathological variant c.1024G>A in the SIL1 gene causing Marinesco-Sjögren syndrome
Marinesco-Sjögren syndrome (MSS) is a rare autosomal recessive neuromuscular disease. MSS patients suffer from ataxia, muscle weakness and cataracts; mental retardation and skeletal abnormalities are often present. In many cases the syndrome is caused by loss of function variant in the SIL1 gene, wh...
ORGANISM(S): Homo sapiens (Human) 
2025-12-22 | PXD062620 | Pride
Sil1 Rare disease Marinesco-sjögren syndrome Proteomics Vus 
UnknownAn Optimized NGS Workflow Defines Genetically Based Prognostic Categories for Patients with Uveal Melanoma.
Not available
S-EPMC11763870 | biostudies-literature
ProteomicsStructural obstruction to full DNA replication in the chromatin of terminally differentiated skeletal muscle cells
Terminal cell differentiation is often associated with permanent withdrawal from proliferation, termed the postmitotic state. Though widespread among vertebrates and determinant for their biology, the molecular underpinnings of this state are poorly understood. Postmitotic skeletal muscle myotubes c...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-01-13 | MSV000096839 | MassIVE
UnknownAnalysis of survival rate and persistence predictors of baricitinib in real-world data from a large cohort of rheumatoid arthritis patients.
Not available
S-EPMC10899020 | biostudies-literature
ProteomicsSILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers
Abstract: Proteomics has been successfully used for cell culture on dishes, but more complex cellular systems have proven to be challenging and so far poorly approached with proteomics. Because of the complexity of the angiogenic program, we still do not have a complete understanding of the molecula...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-02 | MSV000079883 | MassIVE
TranscriptomicsTranscription profiling of human thyrocytes stably expressing wild type RET/PTC1 oncogene or RET/PTC1 carrying Y451F mutation and parental thyrocytes
Mass populations of thyrocytes stably expressing wild type RET/PTC1 oncogene or RET/PTC1 carrying Y451F mutation and parental thyrocytes were used for hybridization on Affymetrix HG-U133A and HG-U133B chips. For each cell condition were generated two different targets (indicated as two different sam...
ORGANISM(S): Homo sapiens 
2005-09-30 | E-MEXP-429 | biostudies-arrayexpress
UnknownErgonomics in the operating room and surgical training: a survey on the Italian scenario.
Not available
S-EPMC11337608 | biostudies-literature
UnknownAccuracy of the clinical diagnosis of dementia with Lewy bodies (DLB) among the Italian Dementia Centers: a study by the Italian DLB study group (DLB-SINdem).
Not available
S-EPMC9213280 | biostudies-literature
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