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TranscriptomicsDichlorvos exposure results in large scale disruption of energy metabolism in the liver of the zebrafish, Danio rerio
Background: Exposure to dichlorvos (DDVP), an organophosphorus pesticide, is known to result in neurotoxicity as well as other metabolic perturbations. However, the molecular causes of DDVP toxicity are poorly understood, especially in cells other than neurons and muscle cells. To obtain a better un...
ORGANISM(S): Danio rerio 
2015-11-05 | E-GEOD-66257 | biostudies-arrayexpress
ProteomicsDichlorvos-induced formation of isopeptide crosslinks between proteins in SH-SY5Y cells
Chlorpyrifos oxon catalyzes the crosslinking of proteins via an isopeptide bond between lysine and glutamic acid or aspartic acid in studies with purified proteins. Our goal was to determine the crosslinking activity of the organophosphorus pesticide, dichlorvos. We developed a protocol for examini...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD033593 | Pride
Shsy5y human neuroblastoma cells Dichlorvos Mass spectrometry Manual evaluation Protein prospector Crosslink Isopeptide Crosslinks 
GenomicsImpact of Dichlorvos on Expression of Superoxide Dismutase in
Impact of dichlorvos on expression of SOD
PRJEB96396 | ENA
TranscriptomicsTranscription profiling of Caenorhabditis elegans treated with Dichlorvos and fenamiphos, to investigate it as a genomic model for toxicology
Effective toxicological testing of the vast number of new and existing chemicals currently in use will require efficient and cost effective methods. We evaluated the utility of a simple, low cost toxicity testing system employing the nematode Caenorhabditis elegans to identify toxicologically releva...
ORGANISM(S): Caenorhabditis elegans 
2009-06-24 | E-GEOD-12298 | biostudies-arrayexpress
GenomicsTranscriptome profile of Trichoderma asperellum challenged with Organophosphorus Pesticide Dichlorvos
Transcriptome profile of Trichoderma asperellum challenged with Organophosphorus Pesticide Dichlorvos
PRJNA470572 | ENA
TranscriptomicsTranscriptome profile of Trichoderma asperellum challenged with Organophosphorus Pesticide Dichlorvos
We report the application of RNA sequencing technology for transcriptome profiling of Trichoderma asperellum challenged with Organophosphorus Pesticide Dichlorvos. Based on RNA-seq analysis, in T. asperellum TJ01 treated with 100 μg/mL, 500 μg/mL, and 1000 μg/mL dichlorvos, 204, 490, and 872 genes w...
ORGANISM(S): Trichoderma asperellum 
2018-07-19 | GSE114217 | GEO
UnknownOmics for understanding the tolerant mechanism of Trichoderma asperellum TJ01 to organophosphorus pesticide dichlorvos.
Not available
S-EPMC6083568 | biostudies-literature
UnknownDichlorvos-induced formation of isopeptide crosslinks between proteins in SH-SY5Y cells.
Not available
S-EPMC10368009 | biostudies-literature
ProteomicsDetection of Dichlorvos Aducts in Hepatocyte Cell Line LC-MS/MS
Toxicity of dichlorvos (DDVP), an organophosphate (OP) pesticide, classically results from modification of the serine in the active sites of cholinesterases. However, DDVP also forms adducts on unrelated targets such as transferrin and albumin, suggesting that DDVP causes cellular perturbation by mo...
ORGANISM(S): Homo sapiens (Human) 
2014-07-31 | PXD001107 | Pride
Hepatocyte cell line Dichorvos Lc-ms/ms 
UnknownMolecular dynamics simulations of acylpeptide hydrolase bound to chlorpyrifosmethyl oxon and dichlorvos.
Not available
S-EPMC4394528 | biostudies-literature
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