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TranscriptomicsTranscription profiling of Dictyostelium discoideum strains lacking the DimB or MybE transcriptions factors in response to treatment with the polyketide DIF-1
The prototypic prestalk-specific gene ecmA is inducible by the polyketide DIF-1. The DimB and MybE transcription factors bind to sites in the ecmA promoter and DIF-1 induction of ecmA in a monolayer assay is greatly diminished in null strains for either of the two factors. We perform genome-wide mic...
ORGANISM(S): Dictyostelium discoideum 
2010-06-09 | E-TABM-804 | biostudies-arrayexpress
TranscriptomicsA Dictyostelium SH2 domain adaptor protein required for correct DIF-1 signaling and pattern formation
When developing in the light slug formation in LrrB null (lrrB-) mutants is delayed, relative to the parental strain, and the slugs are highly defective in phototaxis and thermotaxis. In the dark the mutant arrests development as an elongated mound, in a novel process we term dark stalling. The deve...
ORGANISM(S): Dictyostelium discoideum 
2011-05-31 | E-TABM-1090 | biostudies-arrayexpress
ProteomicsDifferentiation-inducing factor (DIF) SILAC
A global quantitative screen for phosphorylation changes that occur within the first minutes after addition of DIF-1 (differentiation inducing factor) to Dictyostelium cells, using a triple-label SILAC approach. Ax2 cells were labelled in light, medium and heavy medium then starved (5 hr) before DIF...
ORGANISM(S): Dictyostelium discoideum (Slime mold) 
2015-01-28 | PXD001555 | Pride
Dictyostelium Silac Phosphorylation Dif-1 
UnknownThe Dictyostelium prestalk inducer differentiation-inducing factor-1 (DIF-1) triggers unexpectedly complex global phosphorylation changes.
Not available
S-EPMC4325849 | biostudies-literature
UnknownBr-DIF-1 accelerates dimethyl sulphoxide-induced differentiation of P19CL6 embryonic carcinoma cells into cardiomyocytes.
Not available
S-EPMC3312485 | biostudies-literature
UnknownDefects in the synthetic pathway prevent DIF-1 mediated stalk lineage specification cascade in the non-differentiating social amoeba, Acytostelium subglobosum.
Not available
S-EPMC4058090 | biostudies-literature
UnknownA Dictyostelium SH2 adaptor protein required for correct DIF-1 signaling and pattern formation.
Not available
S-EPMC3085826 | biostudies-literature
TranscriptomicsCytoplasmic Control of Plastid Retrograde Signaling by SCFDIF-Mediated Degradation of DIFFERENTIATION AND GREENING-LIKE
Purpose: In plants, chloroplasts not only fix energy through photosynthesis, but they synthesize numerous metabolites which can act as important growth regulators by impacting nuclear gene expression. Upon developmental and external stimuli, signaling between the nucleus and chloroplasts is essentia...
ORGANISM(S): Arabidopsis thaliana 
2018-12-31 | GSE84607 | GEO
UnknownEster derivatives of Dictyostelium differentiation-inducing factors exhibit antibacterial activity, possibly via a prodrug-like function.
Not available
S-EPMC11776220 | biostudies-literature
UnknownDifferentiation-inducing factor-1 suppresses cyclin D1-induced cell proliferation of MCF-7 breast cancer cells by inhibiting S6K-mediated signal transducer and activator of transcription 3 synthesis.
Not available
S-EPMC6890445 | biostudies-literature
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