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Missing values in proteomic data sets have real consequences on downstream data analysis and reproducibility. Although several imputation methods exist to handle missing values, no single imputation method is best suited for a diverse range of data sets, and no clear strategy exists for evaluating i...
ORGANISM(S): Homo sapiens (Human) 
2021-05-07 | PXD023012 | Pride
Different sample preparation methods were tested for HeLa proteome analysis. A sample obtained using sodium deoxycholate-based lysis allowed identification of the highest number of proteins. For this sample, a dilution series was acquired in triplicates ranging from 0.2ng to 200ng. All measurements ...
ORGANISM(S): Homo sapiens (Human) 
2022-06-20 | PXD029836 | Pride
Allelic dilution series series of C57BL6/J:CAST/EiJ RNA using Smart-seq3
This data is part of a large-scale platform comparison experiment. Whole mouse and adult mouse colon RNA was mixed at different concentrations (100:0, 75:25, 50:50, 25:75, and 0:100) and distributed across multiple centers for analysis. Eight microarray platforms and RT-PCR were tested for different...
ORGANISM(S): Mus musculus 
2005-06-30 | GSE2850 | GEO
Genomics
Mock microbial community dilution series
Bacteria transform nutrients and degrade organic matter, making them an essential part of healthy ecosystems. By assaying bacterial physiology within a complex system, the status of the whole ecosystem can be investigated. Proteins are the dynamic molecules that control essential bacterial physiolog...
ORGANISM(S): Ruegeria pomeroyi Thalassiosira pseudonana 
2017-02-01 | PXD004799 | Pride
Bacteria transform nutrients and degrade organic matter, making them an essential part of healthy ecosystems. By assaying bacterial physiology within a complex system, the status of the whole ecosystem can be investigated. Proteins are the dynamic molecules that control essential bacterial physiolog...
ORGANISM(S): Ruegeria pomeroyi 
2017-02-02 | PXD004758 | Pride
The use of custom-made focused microarrays has become a popular alternative, allowing the study of genes relevant to a specific hypothesis. To address the limitations of commercial arrays in toxicogenomics investigations, we have developed a custom mouse oligonucleotide microarray, the HC ToxArrayTM...
ORGANISM(S): Mus musculus 
Genomics
TP53-mutated dilution series
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