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ProteomicsMachine learning from large-scale proteomics accurately ranks anti-cancer drugs based on efficacy
We present an approach, named Drug Ranking Using ML (DRUML), which uses omics data to produce ordered lists of > 400 drugs based on their effectiveness in decreasing cancer cell proliferation. We trained and validated DRUML using in-house proteomics and phosphoproteomics data from a panel of 26 AML,...
ORGANISM(S): Homo sapiens (Human) 
2021-02-22 | PXD019591 | Pride
Cancer Proteomics Drug efficacy prediction Druml Machine learning Phosphoproteomics Drug ranking 
UnknownDrug ranking using machine learning systematically predicts the efficacy of anti-cancer drugs.
Not available
S-EPMC7994645 | biostudies-literature
ProteomicsComputational analysis of cholangiocarcinoma phosphoproteomes identifies patient-specific drug targets
We used mass-spectrometry based phosphoproteomics and computational methods to identify patient-specific drug targets in primary CCA and CCA-derived cell lines. We analyzed 13 primary CCA with matched background tissue and 8 different cell lines leading to the identification and quantification of >1...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD027329 | Pride
Cholangiocarcinoma 
UnknownGenome-Wide Association Studies Based on Equine Joint Angle Measurements Reveal New QTL Affecting the Conformation of Horses.
Not available
S-EPMC6562990 | biostudies-literature
UnknownIdentification of genetic variation on the horse y chromosome and the tracing of male founder lineages in modern breeds.
Not available
S-EPMC3616054 | biostudies-literature
UnknownHigh-resolution population structure and runs of homozygosity reveal the genetic architecture of complex traits in the Lipizzan horse.
Not available
S-EPMC6402180 | biostudies-literature
UnknownGenetic diversity, population structure and subdivision of local Balkan pig breeds in Austria, Croatia, Serbia and Bosnia-Herzegovina and its practical value in conservation programs.
Not available
S-EPMC3311151 | biostudies-literature
UnknownAnalysis of ROH patterns in the Noriker horse breed reveals signatures of selection for coat color and body size.
Not available
S-EPMC6617995 | biostudies-literature
UnknownComputational Analysis of Cholangiocarcinoma Phosphoproteomes Identifies Patient-Specific Drug Targets.
Not available
S-EPMC9397618 | biostudies-literature
UnknownAcetate-buffered crystalloid infusate versus infusion of 0.9% saline and hemodynamic stability in patients undergoing renal transplantation : Prospective, randomized, controlled trial.
Not available
S-EPMC5599439 | biostudies-literature
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