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MetabolomicsBrown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network. Using metabolomics, we identify 3-methyl-2-oxovaleric acid,...
2022-03-03 | MTBLS2436 | MetaboLights
ProteomicsComparative analyses of vertebrate CPEB-family of proteins define two sub-families with distinct, but coordinated, functions in post-transcriptional regulation of gene expressionComparative analyses of vertebrate CPEB-family of proteins define two sub-families with distinct, but coordinated, functions in post-transcriptional regulation of gene expression
Background: The vertebrate CPEB-family of RNA-binding proteins promote translational repression or activation of their target mRNAs, which harbor cytoplasmic polyadenylation elements (CPEs) in their 3’ UTRs, through cytoplasmic changes in their poly(A) tail lengths. However, their regulation(s) and ...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2022-10-05 | PXD030480 | Pride
Mrna translation Deadenylation Cpeb Phosphorylation Ccr4-not complex Phase-separation Bioid 3’utr 
ProteomicsAn Intra-Individual Paired Mass Spectrometry dataset for decoding Solar-Induced Proteomic Changes in Facial Skin
Photoaging is the premature aging of the skin caused by prolonged exposure to solar radiation. The visual alterations manifest as wrinkles, reduced skin elasticity, uneven skin tone, as well as other signs that surpass the expected outcomes of natural aging. Beyond these surface changes, there is a ...
ORGANISM(S): Homo sapiens (Human) 
2024-04-04 | PXD045887 | Pride
Photoaging Skin Proteomics Solar radiation 
ProteomicsUnbiased Proteomic Approach Reveals Rejuvenation-Associated Effects of Quinoa Bioester on Skin
We investigated the effects of a quinoa bioester in topical formulations on skin aging. Sixty-one female participants, one for each age between 20 and 80 years, with Fitzpatrick skin types IV or lower, underwent a 30-day treatment on the volar forearm. Skin samples were collected before and after tr...
ORGANISM(S): Homo sapiens (Human) 
2026-03-16 | PXD062216 | Pride
Quinoa bioester Proteomics Mass spectrometry Support vector regression Skin Aging 
UnknownExtended pharmacological thromboprophylaxis and clinically relevant venous thromboembolism after major abdominal and pelvic surgery: international, prospective, propensity score-weighted cohort study.
Not available
S-EPMC11894929 | biostudies-literature
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