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ProteomicsPost-covid surgical complications in adipose tissue
Spinal cord injury (SCI) patients who underwent reconstructive surgery for pressure ulcers (PU) within 4 weeks of positive SARS-CoV-2 diagnosis were included in this study. Patient’s post-operative progression was registered, while the adipose tissue surrounding the ulcers was analyzed by proteomic ...
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD031241 | Pride
Covid-19 Spinal cord injury Surgery Sars-cov-2 Adipose tissue Pressure ulcers Lc-ms/ms 
ProteomicsThe serum of COVID-19 asymptomatic patients in circulating angiogenic cells ex-vivo
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has provoked, up to date, more than 5 million deaths worldwide. While asymptomatic individuals are responsible of many potential transmissions, the difficulty to identify and isolate them at the high peak of infection constitut...
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD030860 | Pride
Covid-19 Asymptomatic Proteomics Endothelial dysfunction Circulating angiogenic cells Sars-cov-2 Endothelial progenitor cells 
ProteomicsLong-term changes following pre-conditioned circulating angiogenic cells therapy in critical limb ischemia
Critical limb ischemia (CLI), results from a severe blockade of the arterial vessels, is usually correlated to atherosclerosis. Circulating angiogenic cells (CACs) constitute a good alternative as CLI cell therapy due to their vascular regenerative potential, although the mechanisms of action of the...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-16 | PXD024132 | Pride
Neovascularization Circulating angiogenic cells Immune cells Atherosclerotic secretome Critical limb ischemia 
ProteomicsAtherosclerotic environment effect over CAC pre-angiogenic role
In response to vascular injury, early EPC or Circulating angiogenic cells (CAC) are thought to be recruited to the damaged areas, participating mainly in a paracrine fashion, by releasing pro-angiogenic factors, promoting the mobilization of other cell populations such as the late EPC, or endothelia...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD019395 | Pride
Proteomics Angiogenesis Circulating angiogenic cells Atherosclerotic factors Paracrine role Endothelial colony forming cells Secretome 
ProteomicsIdentification of the initial molecular changes in response to Circulating Angiogenic Cells-mediated therapy in Critical Limb Ischemia
Circulating angiogenic cells (CACs) constitute promising candidates for cell therapy in critical limb ischemia (CLI) due to their assigned vascular regenerative properties. A label free MS-based quantitative approach was performed to identify protein changes related. We analyzed the initial molecula...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-27 | PXD017661 | Pride
Critical limb ischemia Angiogenesis Circulating endothelial cells Mouse Cell movement 
ProteomicsGlucagon secretion requires IDE cilium axis
Hyglucagonemia is a hallmark of diabetes caused by dysregulation of glucagon secretion by pancreatic alpha-cells. Although glucose sensing and insulin signaling are well-established regulators, the pathways governing glucagon secretion are not fully understood. Recent evidences suggest that insulin-...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-23 | PXD065342 | Pride
Insulin-degrading enzyme-primary cilium axis Glucagon 
UnknownHeterogeneity in the association between prediabetes categories and reduction on glomerular filtration rate in a 5-year follow-up.
Not available
S-EPMC9072306 | biostudies-literature
UnknownThe heterogeneity of reversion to normoglycemia according to prediabetes type is not explained by lifestyle factors.
Not available
S-EPMC8102601 | biostudies-literature
UnknownDevelopment and validation of a prediction model for 30-day mortality in hospitalised patients with COVID-19: the COVID-19 SEIMC score.
Not available
S-EPMC7908055 | biostudies-literature
UnknownGenotyping, sequencing and analysis of 140,000 adults from Mexico City.
Not available
S-EPMC10600010 | biostudies-literature
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