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GenomicsChIPseq analysis of MYST5 (cg1894) in Drosophila S2 cells
We report here the genome-wide localization of the histone acetyltransferase MYST5 (cg1984) in Drosophila. ChIP-seq analysis was performed with two anti-MYST5 antibodies in S2 cells. We found MYST5 to bind to the promoters of actively transcribed genes. MYST5 furthermore showed extensive colocalizat...
ORGANISM(S): Drosophila melanogaster 
2016-02-23 | E-GEOD-66212 | biostudies-arrayexpress
TranscriptomicsA link between Sas2-mediated H4 K16 acetylation, chromatin assembly in S-phase by CAF-I and Asf1, and nucleosome assembly by Spt6 during transcription
The histone acetyltransferase Sas2 is part of the SAS-I complex and acetylates lysine 16 of histone H4 (H4 K16Ac) in the genome of Saccharomyces cerevisiae. Sas2-mediated H4 K16Ac is strongest over the coding region of genes with low expression. However, it is unclear how Sas2-mediated acetylation i...
ORGANISM(S): Saccharomyces cerevisiae 
2015-09-14 | E-MTAB-2638 | biostudies-arrayexpress
UnknownWerner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells.
Not available
S-EPMC6435321 | biostudies-literature
ProteomicsCross-linking/mass spectrometry analysis of the AOC complex
As a part of a study on how kinetochors are assembled at the centromeres of the chromosomes, cross-linking/mass spectrometry has been applied to investigate interactions between Okp1/ Ame1 heterodimer, which is part of the COMA complex, and CENP-A from Saccharomyces cerevisiae.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-10-30 | PXD009648 | Pride
Protein interaction Cenp-a Okp1 Centromere Cross-linking/mass spectrometry Ame1 
UnknownMechanism and biological role of Dnmt2 in Nucleic Acid Methylation.
Not available
S-EPMC5699548 | biostudies-literature
UnknownA role for β-1,6- and β-1,3-glucans in kinetochore function in Saccharomyces cerevisiae.
Not available
S-EPMC11221361 | biostudies-literature
UnknownDesign of a minimal silencer for the silent mating-type locus HML of Saccharomyces cerevisiae.
Not available
S-EPMC3001064 | biostudies-literature
UnknownVariants of the Sir4 Coiled-Coil Domain Improve Binding to Sir3 for Heterochromatin Formation in Saccharomyces cerevisiae.
Not available
S-EPMC5386860 | biostudies-literature
UnknownMethylation of CENP-A/Cse4 on arginine 143 and lysine 131 regulates kinetochore stability in yeast.
Not available
S-EPMC10078908 | biostudies-literature
ProteomicsCross-linking mass spectrometry of the CCAN and CCAN-Cenp-A complexes
Here we performed a cross-linking mass spectrometry analysis of the inner kinethocore complex CCAN and of the complex associated with a CenpA-nucleosome (CCAN-CenpA)from budding yeast. These experiments validated the cryo-EM structure of both complexes and provided additional structural insights on ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-08-20 | PXD013769 | Pride
S.cerevisiae Cryo-em structure Inner kinetochore complex Xl-ms 
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