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UnknownA Randomized Trial of Zoledronic Acid to Prevent Bone Loss in the First Year after Kidney Transplantation.
Not available
S-EPMC6362629 | biostudies-literature
ProteomicsHost-microbiota interactions in the pathogenesis of antibiotic-associated diseases:Streptomycin plus Salmonella
Improved understanding of the interplay between host and microbes stands to illuminate new avenues for disease diagnosis, treatment and prevention. Here, we provide a high-resolution view of the dynamics between host and gut microbiota during antibiotic induced intestinal microbiota depletion, oppor...
ORGANISM(S): Mus musculus (Mouse) 
2016-02-04 | PXD003152 | Pride
Inflammation Gut Antibiotic Mouse Pathogen Microbiome 
ProteomicsDiversity in pervasive translation. A new translational landscape of yeast.
Pervasive translation is a widespread phenomenon that plays an important role in de novo gene birth; however, its underlying mechanisms remain unclear. Based on multiple Ribosome Profiling datasets, we investigated the translational landscape of coding and noncoding regions of yeast. Therefore, we d...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-09-04 | PXD040766 | Pride
Genome evolution Mass spectrometry Non-canonical translation signals De novo coding products Noncoding genome Pervasive translation 
ProteomicsMHC class I loaded ligands from breast cancer cell lines: A potential HLA-I-typed antigen collection
We sought to build a catalog of epitopes presented by breast cancers using a renewable resource of well-characterized breast cancer cell lines. Starting from 70 breast cancer cell lines, we measured MHC class I abundance and used pre-existing RNAseq data to identify either HLA-A*02 or MHC class I-po...
ORGANISM(S): Homo sapiens (Human) 
2018-01-16 | PXD006406 | Pride
Immune system Mass spectrometry Human Mhc class 1 ligands Hla typing Peptide sequencing Breast cancer Cell lines Immunoprecipitation Rna-seq 
MetabolomicsFeatures of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study
Post-acute sequelae of SARS-CoV-2 (PASC) is a significant public health concern. We describe Patient Reported Outcomes (PROs) on 590 participants prospectively assessed from hospital admission for COVID-19 through one year after discharge. Modeling identified 4 PRO clusters based on reported deficit...
2024-01-12 | MTBLS850 | MetaboLights
TranscriptomicsVIA of EM CD8 T cells in vaccinated monkeys
The goal of an effective AIDS vaccine is to generate immunity that will prevent HIV-1 acquisition. Despite limited progress towards this goal, renewed optimism has followed the recent success of the RV144 vaccine trial in Thailand. However, the lack of complete protection in this trial suggests th...
ORGANISM(S): Macaca mulatta 
2012-06-14 | E-GEOD-35628 | biostudies-arrayexpress
ProteomicsComponents of an ESCRT-independent nuclear envelope assembly pathway
In many cells, the nuclear envelope (NE) must be reassembled after mitosis and holes in the nuclear membrane must be "sealed." During NE assembly, the NE-specific adaptor, Cmp7, recruits/activates ESCRT-III proteins to mediate NE sealing. However, recent evidence suggests the presence of additional ...
ORGANISM(S): Schizosaccharomyces japonicus 
2026-09-12 | PXD082920 | Pride
Ne assembly Nuclear envelope Escrt Membrane remodeling 
ProteomicsProtein aggregation mediates protein complex stoichiometry in aneuploid cells, part 7
Aneuploidy, a condition characterized by chromosome gains and losses, causes reduced fitness and numerous cellular stresses, including increased protein aggregation. Here, we identify protein complex stoichiometry imbalances as a major cause of protein aggregation in aneuploid cells. Subunits of pro...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-05-26 | PXD011916 | Pride
Yeast Proteostasis Aneuploidy Aggregate 
ProteomicsProtein aggregation mediates protein complex stoichiometry in aneuploid cells, part 6
Aneuploidy, a condition characterized by chromosome gains and losses, causes reduced fitness and numerous cellular stresses, including increased protein aggregation. Here, we identify protein complex stoichiometry imbalances as a major cause of protein aggregation in aneuploid cells. Subunits of pro...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-05-26 | PXD011915 | Pride
Yeast Aggregates Proteostasis Aneuploidy 
ProteomicsProtein aggregation mediates protein complex stoichiometry in aneuploid cells, part 4
Aneuploidy, a condition characterized by chromosome gains and losses, causes reduced fitness and numerous cellular stresses, including increased protein aggregation. Here, we identify protein complex stoichiometry imbalances as a major cause of protein aggregation in aneuploid cells. Subunits of pro...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-05-26 | PXD011877 | Pride
Yeast Proteostasis Aneuploidy Aggregate 
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