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ProteomicsUSP18 interactor and PTM mass spectrometry
The ubiquitin-like protein ISG15 is activated in response to type 1 interferons and its conjugation to proteins regulates the response to bacterial and viral infection. Its subsequent deconjugation, by a single human enzyme, USP18, critically controls interferon signaling and the defense against pat...
ORGANISM(S): Homo sapiens (Human) 
2025-07-14 | PXD058618 | Pride
Usp41 Isg15 Deisgylation Deubiquitinase Usp18 
ProteomicsUSP37 prevents unscheduled replisome unloading through MCM complex deubiquitination
The CMG helicase (CDC45-MCM2-7-GINS) unwinds DNA as a component of eukaryotic replisomes. Replisome (dis)assembly is tightly coordinated with cell cycle progression to ensure genome stability. However, factors that prevent premature CMG unloading and replisome disassembly are poorly described. Since...
ORGANISM(S): Homo sapiens (Human) 
2025-05-16 | PXD061463 | Pride
Usp37 Cell cycle Ubiquitin Dna replication Replisome 
UnknownMass spectrometry-based selectivity profiling identifies a highly selective inhibitor of the kinase MELK that delays mitotic entry in cancer cells.
Not available
S-EPMC7039562 | biostudies-literature
UnknownRole of imaging in the staging and response assessment of lymphoma: consensus of the International Conference on Malignant Lymphomas Imaging Working Group.
Not available
S-EPMC5015423 | biostudies-literature
ProteomicsSCFCyclin F targets the metabolic protein Sirtuin 5 for ubiquitination
Cell cycle transitions are regulated by a number of coordinating signaling events. The ubiquitin-proteasome system is an important part of this cell cycle signaling. Cyclin F, a substrate adapter for the SCF (SKP1/CUL1/F-box) E3 ubiquitin ligase, is an important regulator of cell cycle progression. ...
ORGANISM(S): Homo Sapiens (human) 
2020-11-17 | PXD019396 | JPOST Repository
ProteomicsH.sapiens - Cell line, SC (Lyetal.,elife2014)
abundance based on Spectral counting, Interaction consistency score: 24.4, Coverage: 42
ORGANISM(S): 9606 
2014-00-00 | 127272810 | PAXDB
Genomicsena-DATASET-BLUEPRINT-16-01-2015-10:49:23:886-135 - samples
RNAseq profile of purified plasma cells from multiple myeloma patients and tonsils of healthy donors
EGAD00001001212 | EGA
GenomicsBP_August_2015_RNA-Seq_plasma_cell_on_GRCh38 - samples
RNA-Seq data for 4 plasma cell sample(s). 4 run(s), 4 experiment(s), 4 alignment(s) on human genome GRCh38. Part of BLUEPRINT release August 2015. Analysis documentation available at http://ftp.ebi.ac.uk/pub/databases/blueprint/releases/20150820/homo_sapiens/README_rnaseq_analysis_crg_20150820
EGAD00001001523 | EGA
Genomicsena-DATASET-BLUEPRINT-16-03-2018-14:03:53:512-282 - samples
Analysis of the reference epigenomes and regulatory landscape of CLL as a whole and its major clinico-biological subtypes (with mutated and unmutated IGHV) in the light of the normal B-cell differentiation. We have extensively characterized the reference epigenomes of seven primary chronic lymphocy...
EGAD00001004046 | EGA
Genomicsmultiple_myeloma - samples
Purified plasma cells from bone marrow of Multiple myeloma patient
EGAD00010000672 | EGA
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