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MetabolomicsMetabolomic Analysis Reveals an Important Role of Sphingosine 1-phosphate in the Development of HFMD due to EV-A71 Infection

Hand, foot, and mouth disease (HFMD) is a serious pediatric infectious disease that causes immeasurable physical and mental health burdens. Currently, there is a lack of information on the mechanisms of HFMD severity and early diagnosis. We performed metabolomic profiling of sera from 84 Enterovi...

2024-11-14 | MTBLS11656 | MetaboLights
ProteomicsPathological Features of Enterovirus 71-associated Brain and Lung Damage in Mice Based on Quantitative Proteomic Analyses
Enterovirus 71 (EV71), a member of the Enterovirus genus in the Picornaviridae family, was first recognized as a dermotrophic virus that usually cause mild, self-limiting hand-foot-and-mouth disease (HFMD). However, EV71 infection can sometimes induce a variety of severe neurological complications, ...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-10 | PXD023819 | Pride
Enterovirus 71  quantitative proteomics  central nervous system  pulmonary edema  complement and coagulation cascade  type i ifn response 
GenomicsEnterovirus A71
Genome sequencing of human enterovirus 71 from Southeast Asia
PRJNA241017 | ENA
GenomicsEnterovirus A strain:71 | isolate:4643
Uncovering Structural Plasticity of Enterovirus A through Deep Insertional and Deletional Scanning
PRJNA1066851 | ENA
TranscriptomicsScavenger receptor B2 is a cellular receptor for enterovirus 71
Enterovirus 71 (EV71) belongs to human enterovirus species A of the genus Enterovirus within the family Picornaviridae. We established transformant cells by transfection of mouse cells with genomic DNA from human cells and then detected two EV71-susceptible cell lines. Using microarray with the two ...
ORGANISM(S): Mus musculus Homo sapiens 
2009-06-21 | GSE16358 | GEO
TranscriptomicsGene expression profiles of mice dendritic cell infected by Enterovirus 71
Investigate the changes of Gene expression profiling in mice infected with Enterovirus 71 dendritic cell in vitro
ORGANISM(S): Mus musculus 
2021-12-01 | GSE142260 | GEO
GenomicsGene expression profiles of mice dendritic cell infected by Enterovirus 71
Gene expression profiles of mice dendritic cell infected by Enterovirus 71
PRJNA596438 | ENA
ProteomicsGlobal quantitative proteomic analysis of human glioma cells profiled host protein expression in response to enterovirus type 71 infection
Enterovirus 71 (EV71) is one of the leading causes of hand, foot and mouth disease with neurological complications in some cases. To study the pathogenesis of EV71 infection, large scale analyses of EV71 infected cells have been performed. However, most of these studies employed rhabdomyosarcoma (RD...
ORGANISM(S): Homo sapiens (Human) 
2015-09-15 | PXD002454 | Pride
Traf6 Silac Ev71 Quantitative proteomics Traf2 
GenomicsInfection with Enterovirus 71 induces modulation of the microRNA profile of the mouse brain
To further understand the molecular pathogenesis of Enterovirus 71 infection, we profiled cellular microRNAs of brain tissue from suckling Kunming mice infected with EV71 and uninfected mice as comparison.
ORGANISM(S): Mus musculus 
2016-10-23 | GSE89070 | GEO
GenomicsEnterovirus 71 oncolysis of malignant gliomas
Enterovirus 71 oncolysis of malignant gliomas
PRJNA562271 | ENA
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