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ProteomicsIn-Gel digest and filter-aided sample preparation to identify Dermatophagoides - and yeast protein antigens in severe equine asthma.
Severe equine asthma (SEA) is a common, chronic respiratory disease of horses characterized by hyperreactivity to hay dust which has many similarities to severe neutrophilic asthma in humans. A 2D immunoblot approach was used to identify quantitative differences in the recognition of the two-dimensi...
ORGANISM(S): Dermatophagoides Pteronyssinus Saccharomyces Cerevisiae 
2024-01-26 | PXD045568 | panorama
GenomicsEquine serum miRNA in asthma
Equine serum miRNA in asthma
PRJEB16352 | ENA
ProteomicsIn-Gel Digest to identify Aspergillus fumigatus protein antigens in severe equine asthma (SEA)
Aspergillus fumigatus (Asp f) has been described as a major extrinsic stimulus of SEA and is a common mold species in hay. Aiming to identify disease-relevant antigens, we analyzed Asp f as a source, in an immuno-proteomics approach on two-dimensional immunoblots. For 21 of 289 spots serum Ig bindin...
ORGANISM(S): Aspergillus Fumigatus 
PXD045869 | panorama
ProteomicsProteomic Profiling of Equine Airway Mucus Reveals Compositional Changes in Asthmatic Phenotypes
Mucus hypersecretion and accumulation are hallmark features of equine asthma (EA), a meaningful respiratory disorder in horses occurring in mild to moderate (MEA) and severe (SEA) forms. Changes of the proteomic composition of airway mucus in EA are poorly understood. Using label-free quantitative l...
ORGANISM(S): Equus caballus (Horse) 
2025-12-18 | PXD070776 | Pride
Equine asthma Mucus Lc-ms/ms 
UnknownAssociation between equine asthma and fungal elements in the tracheal wash: An environment-matched case-control study.
Not available
S-EPMC11379288 | biostudies-literature
UnknownFlow cytometric analysis of equine bronchoalveolar lavage fluid cells in horses with and without severe equine asthma.
Not available
S-EPMC8679174 | biostudies-literature
MetabolomicsThe transition from winter to spring has an impact on the airway metabolome profile of asthmatic horses

Equine asthma is a chronic, non-infectious inflammatory disease of the lower airways in horses, classified as mild to moderate (MEA) or severe (SEA). Its pathogenesis is not fully understood and is influenced by environmental and seasonal factors. In this cross-sectional study, seasonal effects o...

2026-03-23 | MTBLS13953 | MetaboLights
UnknownGene Expression Profiles of the Immuno-Transcriptome in Equine Asthma.
Not available
S-EPMC9817691 | biostudies-literature
UnknownImpaired response of the bronchial epithelium to inflammation characterizes severe equine asthma.
Not available
S-EPMC5591550 | biostudies-literature
UnknownAn Integrative miRNA-mRNA Expression Analysis Reveals Striking Transcriptomic Similarities between Severe Equine Asthma and Specific Asthma Endotypes in Humans.
Not available
S-EPMC7600650 | biostudies-literature
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