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ProteomicsErythrocyte Membrane Microdomains
Cholesterol-rich microdomains are membrane dynamic compartments characterized by specific lipid and protein composition and present in all cell types. These assemblies are involved in several biological processes, including infection by intracellular pathogens. This work provides a comprehensive ana...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-11-05 | MSV000086413 | MassIVE
ProteomicsQuantitative Analysis of the erythrocyte membrane proteins in polycythemia vera patients treated with hydroxycarbamide
Polycythemia vera (PV) is a myeloproliferative disorder arising in pluripotent stem cells that causes an abnormal erythrocyte mass. More than 90% of PV patients have a mutation in JAK2 protein that is closely associated with the erythrocyte membrane. We report findings on quantitative analysis of th...
ORGANISM(S): Homo sapiens (Human) 
2015-05-11 | PXD001532 | Pride
Polycythemia vera Erythrocyte membrane associated proteins Jak2 v617f Lc-ms/ms 
ProteomicsSickle cell trait modulates the proteome and phosphoproteome of Plasmodium falciparum-infected erythrocyte
The high prevalence of sickle cell disease in some human populations likely results from the protection afforded against severe Plasmodium falciparum malaria and death by heterozygous carriage of HbS. P. falciparum remodels the erythrocyte membrane and skeleton, displaying parasite proteins at the e...
ORGANISM(S): Homo sapiens (Human) Plasmodium falciparum (isolate 3D7) 
2021-04-19 | PXD023280 | Pride
Plasmodium falciparum Membrane phosphorylation Erythrocyte Hemoglobin s Proteomics. 
ProteomicsCytoplasmic erythrocyte proteome in Diamond Blackfan Anemia
Diamond Blackfan Anemia (DBA) is a rare, congenital erythrocyte aplasia that is usually caused by haploinsufficiency of ribosomal proteins due to diverse mutations in one of several ribosomal protein genes. A striking feature of this disease is that a range of different mutations in ribosomal prote...
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD002339 | Pride
Human Erythrocyte Lc-ms/ms 
TranscriptomicsEpigenetic marks reduce erythrocyte uptake of antimalarials
Acquired antimalarial drug resistance produces treatment failures and has led to periods of global disease resurgence. In P. falciparum, resistance is known to arise through genome-level changes such as mutations and gene duplications. We now report an epigenetic resistance mechanism involving genes...
ORGANISM(S): Plasmodium falciparum 
2013-06-03 | E-GEOD-47579 | biostudies-arrayexpress
TranscriptomicsHigh resolution methylome analysis reveals widespread functional hypomethylation during adult human erythropoiesis
Differentiation of hematopoietic stem cells to red cells requires coordinated expression of numerous erythroid genes. To understand the regulatory mechanisms governing lineage commitment we conducted a high resolution methylomic and transcriptomic analysis of six major stages of human erythroid diff...
ORGANISM(S): Homo sapiens 
2013-02-05 | E-GEOD-44054 | biostudies-arrayexpress
UnknownStorage-induced changes in erythrocyte membrane proteins promote recognition by autoantibodies.
Not available
S-EPMC3411782 | biostudies-literature
UnknownProteome analysis of the triton-insoluble erythrocyte membrane skeleton.
Not available
S-EPMC4619114 | biostudies-literature
UnknownErythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform.
Not available
S-EPMC3131364 | biostudies-literature
ProteomicsEffects of G6PD deficiency on the phosphorylation and carbonylation of membrane protein complexes of human erythrocytes infected with Plasmodium falciparum
The ancestral parasite-host relationship associated with human malaria has driven the emergence of mutations in genes, such as erythrocyte glucose-6-phosphate dehydrogenase (G6PD), that confer resistance to lethal malaria and enhance human survival. Protein complexes in the erythrocyte membrane play...
ORGANISM(S): Homo sapiens (Human) Plasmodium falciparum 
2026-09-28 | PXD061301 | Pride
Carbonylation G6pd Phosphorylation Timstof Plasmodium falciparum exportome Blue native 
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