Explant culture

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CHEBI ID

CHEBI:28300 (2)
CHEBI:85363 (1)
CHEBI:41253 (1)
CHEBI:38263 (1)
CHEBI:53210 (1)
CHEBI:6824 (1)
CHEBI:27856 (1)
CHEBI:17790 (1)
CHEBI:70959 (1)
CHEBI:73024 (1)
CHEBI:16977 (1)
CHEBI:422 (1)
CHEBI:18183 (1)
CHEBI:17858 (1)
CHEBI:21557 (1)
CHEBI:89843 (1)
CHEBI:29864 (1)
CHEBI:16467 (1)
CHEBI:9349 (1)
CHEBI:17634 (1)
CHEBI:16680 (1)
CHEBI:7563 (1)
CHEBI:16643 (1)
CHEBI:15603 (1)
CHEBI:16283 (1)
CHEBI:36313 (1)
CHEBI:16856 (1)
CHEBI:16027 (1)
CHEBI:17822 (1)
CHEBI:7916 (1)

Metabolite Name

Theronine (1)
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L-Leucine (1)
L-Tryptophan (1)
L-Histidine (1)
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First Public Date

2014 (23)
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2015 (3)
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2013 (1)

Modification

0.984016 (1)
4 (1)
57.021464 (1)

Study type

Transcription profiling by array (58)
RNA-seq of coding RNA (9)
Methylation profiling by array (3)
RNA-seq of coding RNA from single cells (3)
Baseline (1)
Human - Single-cell sequencing (1)
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Single nucleus RNA sequencing (1)

Release Date

2021 (59)
2023 (54)
2022 (52)
2020 (50)
2025 (43)
2018 (40)
2019 (38)
2014 (37)
2024 (35)
2015 (30)
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2011 (11)
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2007 (8)
2009 (6)
2006 (2)
2005 (2)
2004 (1)
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2000 (1)
1999 (1)
1997 (1)

Lab affiliation

Clinical Sciences, Lund University, Sweden (2)
Laboratório de Biotecnologia, Centro de Biociências e Biotecnologia (CBB), Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF), Av. Alberto Lamego, Campos dos Goytacazes, RJ, Brazil. Unidade de Biologia Integrativa, Setor de Genômica e Proteômica, UENF, Campos dos Goytacazes, RJ, Brazil. (2)
Animal Sciences (1)
Centre for Craniofacial and Regenerative Biology, King's College London, Guy's Hospital, United Kingdom (1)
Clinical Sciences, Lund University BMC-C12, Section for Rheumatology & Molecular Skeletal Biology, 22184 Lund, Sweden (1)
Department of Obstetrics and Gynaecology, Faculty of Medical and Health Sciences, The University of Auckland, New Zealand (1)
Department of clinical chemistry, Institute of Biomedicine, The Sahlgrenska Academy at Gothenburg University (1)
Division of Medical Protein Chemistry, Department of Translational Medicine, Lund University, Sweden (1)
Dr.S. UMA Director, National Research Centre for Banana Trichy, Tamil Nadu, India (1)
Head Proteomics Core Facility Medical University of Vienna Clinical Department of Laboratory Medicine (1)
Head of TIssue Engineering Group at the Departmnet of Dentistry (1)
Institute of Ageing and Chronic Disease, University of Liverpool, United Kingdom (1)
Institute of Biomedical Sciences, Department of Cell and Developmental Biology, University of São Paulo, 05508-000 São Paulo, SP, Brazil. (1)
Proteomics Core Facility, Department of Laboratory Medicine, Medical University of Vienna (1)
Research Unit Protein Science, Helmholtz Center Munich, Germany (1)
Unidad de Biología Integrativa, Centro de Investigación Científica de Yucatán, Calle 43, No. 130 Colonia Chuburná de Hidalgo, Mérida CP 97200, Yucatán, México. (1)
University of Piemonte Orientale (1)
Université de Lille - INSERM U1192 - Laboratoire PRISM (1)
Université de Namur - URBC Narilis (1)

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Ex-Vivo Equine Cartilage Explant Osteoarthritis Model - A Metabolomics and Proteomics Study

Osteoarthritis (OA) is an age-related degenerative musculoskeletal disease characterised by loss of articular cartilage, synovitis, abnormal bone proliferation and subchondral bone sclerosis. Underlying OA pathogenesis is yet to be fully elucidated with no OA specific biomarkers in clinical use. Ex-...

2020-09-30 | MTBLS1495 | MetaboLights

Proteomic analysis of dexamethasone effects on cartilage breakdown

An in vitro explant culture model of cartilage breakdown (post-traumatic osteoarthritis), where explant media mimics the synovial fluid. The OA model was induced by cytokine treatment with or without injury and potential therapeutic treatment was investigated by adding dexamethasone. Proteins releas...

ORGANISM(S): Bos taurus (Bovine)

2020-09-14 | PXD020756 | Pride