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A major limitation in quantitative time-course proteomics is the tradeoff between depth-of-analysis and speed-of-analysis. In high complexity, high dynamic samples such as plant extracts, this is tradeoff is especially apparent. To address this, we evaluate multiple composition voltage (CV) High Fie...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-01-26 | PXD038989 | Pride
A major limitation in quantitative time-course proteomics is the tradeoff between depth-of-analysis and speed-of-analysis. In high complexity, high dynamic samples such as plant extracts, this is tradeoff is especially apparent. To address this, we evaluate multiple composition voltage (CV) High Fie...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-01-26 | PXD039004 | Pride
Mutations that introduce premature termination codons (PTCs) within protein-coding genes are associated with incurable and severe genetic diseases. Many PTC-associated disorders are life-threatening and have no approved medical treatment options. Suppressor transfer RNAs (sup-tRNAs) with the capacit...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD044548 | Pride
Organic ultraviolet filters (UVFs) such as avobenzone, octocrylene and oxybenzone, are considered contaminants of concern due to their widespread occurrence in aquatic environments. Previous research has demonstrated that these UVFs are toxic to aquatic invertebrates over single generation exposures...
ORGANISM(S): Daphnia magna 
2025-08-03 | PXD052188 | Pride
non-Hodgkins lymphoma cells were treated with a CDK9 inhibitor to determine which proteins and phosphorylation events are affected by CDK9 in lymphoma.
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD035858 | Pride
D1 ductal cells from human pancreatic exocrine tissue cultured in 2 different conditions, one with a proinflammatory cytokine cocktail and the other as a vehicle control. Observe differences between cyto and control in all samples and then just in the non-obese and non-diabetic group.
ORGANISM(S): Homo sapiens (Human) 
2026-06-24 | PXD074059 | Pride
Bottom-up mass spectrometry-based proteomics is challenged by the task of identifying the peptide that generates a tandem mass spectrum. Traditional methods that rely on known peptide sequence databases are limited and may not be applicable in certain contexts. De novo peptide sequencing, which assi...
ORGANISM(S): Homo sapiens (Human) 
2025-01-07 | PXD044934 | Pride
The CD117 mast/stem cell growth factor receptor tyrosine kinase (KIT) is critical for haematopoiesis, melanogenesis, and stem cell maintenance. KIT is commonly activated by mutation in cancers including acute myeloid leukaemia, melanoma, and gastrointestinal stromal tumours (GISTs). The kinase and t...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-19 | PXD043783 | Pride
Plants, as sessile organisms, require robust responses in protein synthesis to adapt to variable environmental conditions. Measurement of newly synthesized proteins has been successfully facilitated with Bio-Orthogonal Non-Canonical Amino acid Tagging (BONCAT) across a multitude of organisms. Here, ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-06-08 | PXD064210 | Pride
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