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Unnatural monosaccharides such as azidosugars that can be metabolically incorporated into cellular glycans are currently used as a major tool for glycan imaging and glycoproteomic profiling. As a common practice to enhance membrane permeability and cellular uptake, the unnatural sugars are per O ac...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2019-09-09 | PXD015035 | Pride
Unnatural monosaccharides such as azidosugars that can be metabolically incorporated into cellular glycans are currently used as a major tool for glycan imaging and glycoproteomic profiling. As a common practice to enhance membrane permeability and cellular uptake, the unnatural sugars are per O ac...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2019-09-12 | PXD014785 | Pride
In our previous study, we uncovered that OGA significantly elevated in naïve hESC. Therefore, we sought to investigate the effects of O-GlcNAc on hESC and the interconvert of both pluripotent states. Depletion of OGA, which results in global O-GlcNAcylation increased, would impair naïve hESC pluripo...
ORGANISM(S): Homo sapiens (Human) 
2024-08-10 | PXD041605 | Pride
Ligand-stimulated epidermal growth factor receptor (EGFR) signaling plays fundamental roles in normal cell physiology, such as cell growth, cell proliferation, and cell survival. Deregulation of EGFR signaling contributes to the development and progression of diseases including cancer. Despite its e...
ORGANISM(S): Homo sapiens (Human) 
2022-04-04 | PXD031700 | Pride
Candidatus Liberibacter asiaticus (CLas), the causative agent of Citrus Huanglongbing (HLB), disrupts global citrus production through poorly defined mechanisms. Integrated proteomic and ubiquitinomic analyses of CLas-infected Citrus sinensis leaves revealed systemic proteostatic dysregulation. Prot...
ORGANISM(S): Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis) 
2026-09-14 | PXD062872 | Pride
In this project, we used proteomics to identify and compare protein profile changed in SIM-1, MZ-1, or JQ-1 treated TIVE-LTC, a KSHV long-term infected immortalized endothelial cell line.
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD075129 | Pride
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