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ProteomicsMediator Kinase Complexes Regulates ATOH1-Dependent Intestinal Differentiation
Cyclin Dependent Kinases CDK8 and CDK19 (Mediator kinase) are regulatory components of the Mediator complex, a highly conserved complex that fine tunes transcriptional output. While Mediator kinase has been implicated in the transcriptional control of key pathways necessary for development and growt...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-10 | PXD030212 | Pride
Phosphoproetomics. cdk8 Cdk19 
ProteomicsSAPrIm, A Semi-Automated Protocol for mid-throughput Immunopeptidomics
Human leukocyte antigen (HLA) molecules play a crucial role in the development of adaptive immune responses and therefore have been of major interest in the development of immunotherapies such as cancer vaccines and chimeric antigen receptor (CAR) T cells. Hence, a comprehensive understanding and pr...
ORGANISM(S): Homo sapiens (Human) 
2023-05-23 | PXD041046 | Pride
Immunopeptidomics Human leukocyte antigen Kingfisher 
ProteomicsSAPrIm 2.0: A semi-automated protocol for mid-throughput soluble HLA immunopeptidomics
Human leukocyte antigen (HLA) molecules are pivotal in guiding human adaptive immune responses through their presentation of peptide ligands, collectively known as the immunopeptidome. This process is central to the development of cancer immunotherapies, such as vaccines and T-cell therapies. Profil...
ORGANISM(S): Homo sapiens (Human) 
2025-05-26 | PXD058880 | Pride
Shla Hla Mass spectrometry Mhc Saprim Immunopeptidomics Soluble hla Plasma immunopeptidomics 
UnknownAn Ancient Transkingdom Horizontal Transfer of Penelope-Like Retroelements from Arthropods to Conifers.
Not available
S-EPMC4860704 | biostudies-literature
ProteomicsIdentification of immunodominant ERV peptides critical for anti-metastatic immunity in a model of TNBC
The integration of immunotherapy into neoadjuvant treatment for triple negative breast cancer (TNBC) has improved outcomes in some patients. Pre-clinical investigation of immunotherapy resistance in the aggressive 4T1 TNBC model has been hampered by a lack of known tumor-specific epitopes. Using pro...
ORGANISM(S): Homo sapiens (Human) 
2026-09-21 | PXD069588 | Pride
Erv Tnbc Immunopeptidomics 
ProteomicsThe self-peptide repertoire plays a critical role in transplant tolerance induction
While direct allorecognition underpins both solid organ allograft rejection and tolerance induction, the specific molecular targets of most directly-alloreactive CD8+ T cells have not been defined. In this study, we used a combination of genetically-engineered MHC I constructs, mice with a hepatocyt...
ORGANISM(S): Mus musculus (Mouse) 
2021-12-06 | PXD023015 | Pride
Immunopeptidomics Hla Transplantation 
UnknownConformational changes within the HLA-A1:MAGE-A1 complex induced by binding of a recombinant antibody fragment with TCR-like specificity.
Not available
S-EPMC2708021 | biostudies-literature
UnknownMicroBubble activated acoustic cell sorting.
Not available
S-EPMC5378755 | biostudies-literature
UnknownComprehensive molecular cytogenetic analysis of sorghum genome architecture: distribution of euchromatin, heterochromatin, genes and recombination in comparison to rice.
Not available
S-EPMC1456119 | biostudies-literature
UnknownHow large is the periablational zone after radiofrequency and microwave ablation? Computer-based comparative study of two currently used clinical devices.
Not available
S-EPMC7714001 | biostudies-literature
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