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MetabolomicsIntergenerational Association of Gut Microbiota and Metabolism with Perinatal Folate Metabolism and Neural Tube Defects (Brain tissue metabolomics)

Neonatal hypoxic-ischemic encephalopathy (HIE) refers to nervous system damage caused by perinatal hypoxia, which is the major cause of long-term neuro-developmental disorders in surviving infants. However, the mechanisms still require further investigation. In this study, we found that the butan...

2022-12-05 | MTBLS4894 | MetaboLights
MetabolomicsThe rumen metagenome and its metabolome in yaks associated with feeding regime

Background: Grazing yearly on pasture is a traditional practice for yaks, which cannot meet the requirements of yak products since the insufficient forage supplied in the cold season results in a long production cycle. An intensive feeding system increasing production efficiency has been selected...

2024-10-01 | MTBLS10856 | MetaboLights
MetabolomicsTranscriptomic and metabolomic data of Populus deltoides ‘Shalinyang’ (PdS) response to feeding of Anoplophora glabripennis adults
Populus deltoides ‘Shalinyang’ (PdS), a vital species for artificial shelterbelts in the arid regions of northwest China, has shown resistance to the destructive stem-boring beetle Anoplophora glabripennis Motschulsky (Asian longhorned beetle, ALB). However, comprehensive research in this area is st...
2026-03-25 | MTBLS12296 | MetaboLights
ProteomicsLC-MSMS analysis of Meloidogyne incognita feeding tube enriched samples isolated from tobacco and tomato giant cell cytoplasm
Here we developed a protocol for the isolation and semi-purification of root-knot nematode feeding tubes from giant-cell cytoplasm of several host plant species. Our methods allowed for the isolation and solubilization of sufficient quantities of enriched feeding tubes enabling a comparative proteom...
ORGANISM(S): Meloidogyne incognita Nicotiana tabacum (Common tobacco) Solanum lycopersicum 
2026-02-16 | PXD065741 | Pride
Tobacco Tomato Meloidogyne incognita Root-knot nematode Giant cell Feeding tube 
MetabolomicsJejunal inflammatory cytokines, barrier proteins and microbiome-metabolome responses to early supplementary feeding of Bamei suckling piglets

BACKGROUND: Dietary intervention has been reported to improve intestinal health. The intestinal microbiota of newborn animals plays a fundamental role in the development of intestinal function and the innate immune system. However, little is currently known about dietary interven...

2020-06-05 | MTBLS1698 | MetaboLights
MetabolomicsTargeting the gut-lung axis by synbiotic feeding to infants in a randomized controlled trial

Synbiotics may modulate gut microbiota and prevent infections. In a randomized controlled trial (NCT01625273) infants weaned from breast milk were fed formula with prebiotics (fructo- and galactooligosaccharides) or the same prebiotic formula with Lactobacillus paracasei ssp. paracasei s...

2022-11-24 | MTBLS2438 | MetaboLights
MetabolomicsBioaccumulation of therapeutic drugs by human gut bacteria: cross-feeding metabolite analysis (FIA-MS) (E.rectale;S.salivarius assays)

Bacteria in the gut can modulate the availability and efficacy of therapeutic drugs. Interactions at this level have only recently started to being systematically mapped and the main underlying mechanism proposed is chemical transformation of drugs by microbes (biotransformation). Here, we invest...

2021-07-20 | MTBLS1792 | MetaboLights
MetabolomicsCross-feeding and co-degradation within a bacterial consortium dominated by challenging-to-cultivate Leucobacter sp. HA-1 enhances sulfonamides degradation

Background: The use of sulfonamides (SAs) caused residual pollution in the environment. Bacteria play an important role in the degradation of sulfonamide antibiotics, and microbial consortium offers advantages over single bacterium. However, the complex degradation process and interaction mechani...

2024-11-08 | MTBLS11473 | MetaboLights
TranscriptomicsNeonatal antibotic prophylaxis modulates intestinal immunity and prevents necrotizing enterocolitis in preterm neonates
Caesarean-delivered preterm pigs were fed 3 d of parenteral nutrition followed by 2 d of enteral formula feeding. Antibiotics (n=11) or control saline (n=13) were given twice daily from birth to tissue collection at d 5. NEC-lesions and intestinal structure, function, microbiology and immunity marke...
ORGANISM(S): Sus scrofa 
2013-08-21 | E-GEOD-48125 | biostudies-arrayexpress
TranscriptomicsPost-fasting olfactory, transcriptional, and feeding responses in Drosophila
The sensation of hunger after a period of fasting and the sensation of satiety after eating is crucial to behavioral regulation of food intake, but the biological mechanisms regulating these sensations are incompletely understood. We studied the behavioral and physiological adaptation to fasting in ...
ORGANISM(S): Drosophila melanogaster 
2011-09-23 | E-GEOD-27927 | biostudies-arrayexpress
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