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Transcriptomics3C-seq of HT29 cells with CCAT1-L knockdown or scramble knockdown
CCAT1-L is a highly expressed long noncoding RNA located in the colorectal cancer specific super enhance region about 500 kb upstream of MYC gene. Knockdown of CCAT1-L significantly down-regulated interaction frequency between CCAT1 and MYC locus and repress MYC expression, suggesting a long-range c...
ORGANISM(S): Homo sapiens 
2014-02-22 | E-GEOD-55261 | biostudies-arrayexpress
UnknownQi Ling decreases paclitaxel resistance in the human prostate cancer by reversing tumor-associated macrophages function.
Not available
S-EPMC8908933 | biostudies-literature
UnknownTRAF6 polymorphisms not associated with the susceptibility to and severity of sepsis in a Chinese population.
Not available
S-EPMC4129682 | biostudies-literature
TranscriptomicsRNA-seq from paired human CRC/control mucosa samples
We have used RNA-seq to examine gene expression from paired human CRC/control mucosa samples and identified CRC-specific expressed long noncoding RNAs To identify CRC-specific expressed genes, including long noncoding RNAs
ORGANISM(S): Homo sapiens 
2014-02-22 | E-GEOD-55259 | biostudies-arrayexpress
MetabolomicsMetabolome analysis reveal key regulatory pathways of feed conversion efficiency of oriental river prawn Macrobrachium nipponense

A total of 445 and 247 differently expressed metabolites (DEMs) were identified in the hepatopancreas and muscle. In addition, 11 KEGG pathways, which mainly include lysine biosynthesis, lysine degradation, aminoacyl-tRNA biosynthesis and purine metabolism, were sign...

2023-02-28 | MTBLS6663 | MetaboLights
UnknownA Comprehensive Comparative Analysis and Phylogenetic Investigation of the Chloroplast Genome Sequences in Four Astragalus Species.
Not available
S-EPMC12731972 | biostudies-literature
UnknownMETTL3 Modulates Osteoclast Differentiation and Function by Controlling RNA Stability and Nuclear Export.
Not available
S-EPMC7084668 | biostudies-literature
MetabolomicsThe trans-omics landscape of COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
ProteomicsMulti-omics analysis combined with the Nephroseq database reveals that FN1 and three other genes are closely related to renal function in diabetic nephropathy.
Diabetic nephropathy is a serious late chronic complication of type 2 diabetes and a major cause of end-stage renal disease. In order to better understand the molecular mechanisms of kidney lesions, we examined the mRNA and protein levels of mouse kidney to reveal the changes occurring in the kidney...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-10-20 | PXD058790 | Pride
Proteomics Transcriptomics Liraglutide Type 2 diabetes Empagliflozin Diabetic nephropathy 
TranscriptomicsAdipocyte XBP1s regulates systemic insulin sensitivity by modulating adiponectin multimerization
The physiological role of the spliced form of X-box-binding protein 1 (XBP1s), a key transcription factor of the endoplasmic reticulum (ER) stress response, in adipose tissue remains largely unknown. Here we show that overexpression of XBP1s promotes adiponectin multimerization in adipocytes, thereb...
ORGANISM(S): Mus musculus 
2013-11-21 | E-GEOD-36031 | biostudies-arrayexpress
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