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The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights

Gut microbiota dysbiosis has been implicated in pulmonary arterial hypertension (PAH). However, most studies have focused on the bacterial community and the exact role and mechanisms of multi-kingdom gut microbiota, including bacteria, archaea and fungi in PAH remains largely unclear. Idiopathic ...

2025-05-12 | MTBLS10563 | MetaboLights
Acute coronary syndrome (ACS) is a kind of cardiovascular disease caused by acute myocardial ischemia. The aim of this study was to use urine metabolomics to explore the potential biomarkers for the diagnosis of ACS and the changes in metabolites during the development of the disease.
ORGANISM(S): Homo Sapiens 
2024-12-03 | PXD058501 |
This dataset comprises proteomic profiles of 87 human carotid atherosclerotic plaques from patients undergoing carotid endarterectomy (CEA). The study employed an integrated approach using Data Independent Acquisition (DIA) proteomics. A total of 87 human carotid plaques were analyzed to identify an...
ORGANISM(S): Homo Sapiens 
2025-03-26 | PXD062283 |
We provided a comprehensive AH proteome analysis, and expanded the profile of human AH proteome. The differential AH proteomic analysis of NVG treatment indicated that AH proteome can reflect the pathophysiological changes in drug intervention.
ORGANISM(S): Homo Sapiens 
Proteomics Profile of right ventricular remodeling at compensatory stage (both PAB and MCT models)
ORGANISM(S): Rattus Norvegicus 
We analyzed samples of tumor tissue, plasma, and urine from a cohort of 27 ccRCC patients with T1-2 stage and 27 matched healthy controls, using liquid chromatography–mass spectrometry (LC-MS) for proteomic analysis. We integrated the differential proteins found in the three types of samples to expl...
ORGANISM(S): Homo Sapiens 
The N6-methyladenosine (m6A) binding protein YTHDF1 emerges as a frequently upregulated oncogene across various cancer types. Its depletion significantly improves the efficacy of cancer immune checkpoint blockade (ICB) treatment. A comprehensive understanding of the molecular mechanisms governing YT...
ORGANISM(S): Homo Sapiens 
2024-11-14 | PXD057917 |
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