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ProteomicsTemporal modulation of the NF-kB network in response to different types of DNA damage ETOPOSIDE C4PR_LIV
Different types of DNA damage can initiate phosphorylation-mediated signalling cascades that result in stimulus specific pro- or anti-apoptotic cellular responses. Amongst its many roles, the NF-κB transcription factor RelA is central to the DNA damage response pathway. Yet, understanding of the co-...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD019587 | Pride
Dna damage  rela  p65  nf-κb  phosphorylation  mass spectrometry Phosphoproteomics  etoposide  hydroxyurea 
ProteomicsTemporal modulation of the NF-kB network in response to different types of DNA damage HYDROXYUREA C4PR_LIV
Different types of DNA damage can initiate phosphorylation-mediated signalling cascades that result in stimulus specific pro- or anti-apoptotic cellular responses. Amongst its many roles, the NF-κB transcription factor RelA is central to the DNA damage response pathway. Yet, understanding of the co-...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD019589 | Pride
Dna damage  rela  p65  nf-κb  phosphorylation  mass spectrometry Phosphoproteomics  etoposide  hydroxyurea 
ProteomicsIdentification of p115 interacting proteins from HEK293T cells
The protein p115 is a key player in the delivery of vesicles from the endoplasmic reticulum to the early Golgi. The protein is a homodimer with a folded head domain and a coiled-coil tail that is anchored to Golgi membranes. p115 has been shown to capture vesicles and to bind to SNARE proteins to p...
ORGANISM(S): Homo sapiens (Human) 
2026-06-02 | PXD075617 | Pride
Human Lc-msms P115 Uso1 Hek293t Sec16a 
ProteomicsPost-transcriptional glucocorticoid receptor signalling synchronises circadian rhythms
Circadian rhythms are driven by cellular clocks throughout the body that maintain optimal health. Glucocorticoid (GC) hormones are vital for synchronising cellular clocks, aligning them with external day/night cycles, but mechanistic understanding is incomplete. We use a glucocorticoid receptor KO/r...
ORGANISM(S): Homo sapiens (Human) 
2026-09-04 | PXD081613 | Pride
Nuclear hormone receptor Rna processing Circadian rhythm Glucocorticoid Clock synchronisation Entrainment Post-transcriptional regulation 
UnknownEvidence-Based Checklist to Delay Cardiac Arrest in Brain-Dead Potential Organ Donors: The DONORS Cluster Randomized Clinical Trial.
Not available
S-EPMC10722341 | biostudies-literature
UnknownKetamine, Etomidate, and Mortality in Emergency Department Intubations.
Not available
S-EPMC12706683 | biostudies-literature
UnknownDONORS (Donation Network to Optimise Organ Recovery Study): Study protocol to evaluate the implementation of an evidence-based checklist for brain-dead potential organ donor management in intensive care units, a cluster randomised trial.
Not available
S-EPMC6597655 | biostudies-literature
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