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TranscriptomicsRegenerating zebrafish fin fold vs. uncut control
Teleost fish have the remarkable ability to regenerate their body parts including heart, spinal cord, and the caudal fin, while many higher vertebrates including us humans have only a limited ability. To facilitate molecular and genetic approaches for regeneration, we previously established an assay...
ORGANISM(S): Danio rerio 
2010-05-19 | E-GEOD-11391 | biostudies-arrayexpress
ProteomicsEffect of Small Molecules in Zebrafish Caudal Fin Regeneration
The study analysed proteomic changes during zebrafish caudal fin tissue regeneration post small molecule treatment.
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2025-11-24 | PXD060144 | Pride
Regeneration Zebrafish Small molecules 
TranscriptomicsTranscription profiling time series of Danio rerio heart regeneration
Amputation of heart tissue followed by regeneration of the heart. Samples were taken at 0 hpa (hours post-amputation), 6 hpa, 12 hpa, 24 hpa, 3 dpa and 5 dpa.
ORGANISM(S): Danio rerio 
2008-09-05 | E-MEXP-1239 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of zebrafish adult and larval fin to investigate mechanisms of regeneration
Zebrafish have the remarkable ability to regenerate body parts including the heart, spinal cord and fins by a process referred to as epimorphic regeneration. Recent studies have illustrated that similar to adult zebrafish, early life stage-larvae also possess the ability to regenerate the caudal fin...
ORGANISM(S): Danio rerio 
2008-04-07 | E-GEOD-10188 | biostudies-arrayexpress
TranscriptomicsSmall RNA and mRNA expression profiling during zebrafish caudal fin regeneration
Previous studies of zebrafish caudal fin regeneration have shown that multiple genetic programs are moduled through regulatory factors. MicroRNAs are short highly conserved non-coding genes that suppress expression of target genes and thereby control multiple genetic programs. Given their importan...
ORGANISM(S): Danio rerio 
2016-06-01 | E-GEOD-74415 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Zebrafish regenerating caudal fin tissue in the presence and absence of the dioxin TCDD
Adult zebrafish can completely regenerate their caudal fin following amputation. This complex process is initiated by the formation of an epithelial would cap over the amputation site by 12 hours post amputation (hpa). Once the cap is formed, mesenchymal cells proliferate and migrate from sites dist...
ORGANISM(S): Danio rerio 
2007-10-05 | E-GEOD-3667 | biostudies-arrayexpress
TranscriptomicsGene expression data from time course of fin regeneration in Danio rerio (part 1)
Olsen et al (2010) have shown that induced Diabetes mellitus (DM) in adult Zebrafish results in an impairment of tissue regeneration as monitored by caudal fin regeneration. In those studies, streptozocin was used to induce hyperglycemia in adult zebrafish, and then, following streptozocin withdrawa...
ORGANISM(S): Danio rerio 
2012-11-01 | E-GEOD-37163 | biostudies-arrayexpress
TranscriptomicsGene expression data from time course of fin regeneration in Danio rerio (part 2)
Olsen et al (2010) have shown that induced Diabetes mellitus (DM) in adult Zebrafish results in an impairment of tissue regeneration as monitored by caudal fin regeneration. In those studies, streptozocin was used to induce hyperglycemia in adult zebrafish, and then, following streptozocin withdrawa...
ORGANISM(S): Danio rerio 
2012-11-01 | E-GEOD-37164 | biostudies-arrayexpress
ProteomicsUpregulation of protein O-GlcNAcylation levels promotes zebrafish fin regeneration
LC-MS/MS was performed to identify O-GlcNAc-glycoproteins. The results demonstrated that the O-GlcNAc glycoproteins
ORGANISM(S): Danio Rerio 
2025-02-22 | PXD059799 |
ProteomicsGlucocorticoid treatment leads to aberrant ion and macromolecular transport mechanisms in regenerating zebrafish fins.
Bone is a highly regenerative tissue but it can be permanently lost due to severe trauma and as a result of disease. In zebrafish, which are capable of complex organ regeneration, intramembranous bones of the fins and skull regenerate rapidly even after profound loss. The fin regenerate, albeit bein...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2019-09-26 | PXD013552 | Pride
Prednisolone Glucocorticoid Fin regeneration Q exactive hf Lable free quantification Lfq Zebrafish 
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