Sort   by:  
 Page size 
ProteomicsProteomic changes in the hypothalamus after treatment with GLP-1RA, Tesaglitazar, or GLP-1RA/Tesaglitazar (GLP-1RA mediated Tesaglitazar delivery)
The peroxisome proliferator-activated receptors alpha and gamma (PPAR𝛼/𝛾) play important roles in the regulation of energy, lipid and glucose metabolism. Drugs targeting these proteins such as Fibrates and TZDs have both shown beneficial cardiovascular effects in clinical trials, which together wi...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-07 | PXD033653 | Pride
Tesaglitazar Glp-1ra Glp-1 Mouse Hypothalamus Targeted delivery 
ProteomicsAn unimolecular GIPR:GLP-1R:PPAR𝛼,𝛾,𝛿 quintuple agonist eliminates obesity and insulin resistance in mice.
Drugs to improve obesity-linked metabolic dysfunction are on the rise, with GLP-1:GIP co-agonism being effective in the management of obesity and type 2 diabetes, and with Lanifibranor (Lani), a nuclear acting small molecule triple agonist at the peroxisome proliferator-activated receptors alpha, ga...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-14 | PXD062990 | Pride
Gipr Glp1r Obesity 
TranscriptomicsRNA-seq of 1019 human cancer cell lines from the Cancer Cell Line Encyclopedia
RNA-seq of 1019 human cancer cell lines from the Broad-Novartis Cancer Cell Line Encyclopedia (http://www.broadinstitute.org/ccle). The original annotation of each cell line to a disease has been checked and manually curated by Expression Atlas (https://www.ebi.ac.uk/gxa/home). Note the original ver...
ORGANISM(S): Homo sapiens 
2013-05-31 | E-MTAB-2770 | biostudies-arrayexpress
UnknownGLP-1-mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice.
Not available
S-EPMC9398908 | biostudies-literature
UnknownThe Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Not available
S-EPMC3320027 | biostudies-literature
UnknownDiagnostic uncertainty presented barriers to the timely management of acute thrombotic thrombocytopenic purpura in the United Kingdom between 2014 and 2019.
Not available
S-EPMC9314944 | biostudies-literature
UnknownMulti-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification.
Not available
S-EPMC10601987 | biostudies-literature
Unknown2023 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces.
Not available
S-EPMC10713008 | biostudies-literature
UnknownInvestigation of common, low-frequency and rare genome-wide variation in anorexia nervosa.
Not available
S-EPMC5828108 | biostudies-literature
UnknownA genome-wide association study of anorexia nervosa.
Not available
S-EPMC4325090 | biostudies-literature
Sort   by:  
 Page size