Sort   by:  
 Page size 
ProteomicsmiR-17-92 sustains lymphoma growth by fine-tuning MYC
The synergism between c-MYC and miR-17-19b, a truncated version of the miR-17-92 cluster, is well documented during tumor initiation. However, little is known about miR-17-19b function in established cancers. Here we investigate the role of miR-17-19b in c-MYC-driven lymphomas by integrating SILAC-b...
ORGANISM(S): Mus musculus (Mouse) 
2015-11-06 | PXD002810 | Pride
Lc-msms Lymphoma Microrna Myc Mir-17-92 Chek2 
TranscriptomicsAdaptation of Bacillus subtilis carbon core metabolism to simultaneous nutrient limitation and osmotic challenge
Here, we investigated for the first time the systems-wide response of B. subtilis to different simultaneous stresses, i.e. nutrient limitation and high osmolarity. To address the anticipated complexity of the cellular response networks, we combined chemostat experiments under conditions of carbon li...
ORGANISM(S): Bacillus subtilis 
2014-03-31 | E-GEOD-53333 | biostudies-arrayexpress
MetabolomicsMetabolic Dynamics of In Vitro CD8+ T Cell Activation

CD8+ T cells detect and kill virally infected or cancerous cells. When activated from their naïve state, T cells undergo a complex transition, including major metabolic reprogramming. Detailed resolution of metabolic dynamics of a wide range of metabolites is needed to advance the field of immuno...

2021-06-02 | MTBLS2145 | MetaboLights
TranscriptomicsHolo-TFIID controls the magnitude of a transcription burst and fine-tuning of transcription.
TFIID is a central player in activated transcription initiation. Recent evidence suggests that the role and composition of TFIID is more diverse than previously understood. To investigate the effects of changing the composition of TFIID in a simple system we depleted TAF1 from Drosophila cells and d...
ORGANISM(S): Drosophila melanogaster 
2013-05-01 | E-GEOD-45873 | biostudies-arrayexpress
Transcriptomics8-chip high-resolution aCGH experiment NA15510 vs. NA18505
We introduce high-throughput and massive paired-end mapping (PEM), a large-scale genome sequencing method to identify SVs 3 kb or larger that combines the rescue and capture of paired-ends of 3 kb fragments, massive 454 Sequencing, and a computational approach to map DNA reads onto a reference genom...
ORGANISM(S): Homo sapiens 
2007-09-28 | E-GEOD-9002 | biostudies-arrayexpress
UnknownEnhanced aqueous formation and neutralization of fine atmospheric particles driven by extreme cold.
Not available
S-EPMC11421654 | biostudies-literature
ProteomicsEpitope fine mapping by mass spectrometry: Investigations of immune complexes consisting of monoclonal anti-HpTGEKP antibody and zinc finger protein linker phospho-hexapeptides.
We describe the mass spectrometric analysis of the binding strength of a monoclonal mouse antibody (clone 18E9.D9, BioLegend, London, England) which was raised against the predominantly occuring phosphorylated linker sequence, HpTGEKP, of C2H2 zinc finger proteins (ZNF proteins) using a synthetic ...
ORGANISM(S): Homo sapiens (Human) 
2022-08-15 | PXD031150 | Pride
Item-two Off-line esi-ms Zinc finger-phosphopeptide Antiphosphopeptide-antibody Binding strength characterization 
UnknownSynthetic gene circuits for cell state detection and protein tuning in human pluripotent stem cells.
Not available
S-EPMC9650275 | biostudies-literature
UnknownFine mapping of the HLA locus in Parkinson's disease in Europeans.
Not available
S-EPMC8455634 | biostudies-literature
UnknownCommon viral infections inhibit egg laying in honey bee queens and are linked to premature supersedure.
Not available
S-EPMC11283550 | biostudies-literature
Sort   by:  
 Page size