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ProteomicsChemical Denaturation and Protein Precipitation (CPP) on E. coli lysate
Chemical Denaturation and Protein Precipitation (CPP) was performed on an E. coli lysate in order to determine the precipitaiton midpoint for the proteome
ORGANISM(S): Escherichia coli 
2023-01-03 | PXD036219 | Pride
Cpp E. coli Precipitation 
ProteomicsSPROX full curve on E. coli lysate
To probe the thermodynamic stability of proteins within the E. coli proteome through proteomic technique SPROX.
ORGANISM(S): Escherichia coli 
2023-01-03 | PXD035834 | Pride
E. coli Sprox Stability 
ProteomicsMetal-induced Protein Precipitation in E. coli
Using a range of copper we have utilized Metal-induced Protein Precipitaiton (MiPP) technique to elucidate the copper midpoints of the proteins found in an E. coli proteome. Using bottem-up proteomics techniques and TMT-10 plex isobaric mass-tags we were able to use MiPP to classify proteins based o...
ORGANISM(S): Escherichia coli 
2023-01-03 | PXD035711 | Pride
Precipitiation Sprox Cpp Metal E. coli Copper 
TranscriptomicsProstate Cancer CGH in a single large family
For sample information see "High-Density, Genome-Wide Linkage and Gene Copy Number Analyses of a Six-Generation Prostate Cancer Family." by Fitzgerald et al, Cancer Research.
ORGANISM(S): Homo sapiens 
2010-06-11 | E-GEOD-2681 | biostudies-arrayexpress
ProteomicsDiscovery of the Xenon-Protein Interactome using Large-Scale Measurements of Protein Folding and Stability
The intermolecular interactions of noble gases in biological systems are associated with numerous biochemical responses, including apoptosis, inflammation, anesthesia, analgesia, and neuroprotection. The molecular modes of action underlying these responses are largely unknown. This is in large part ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-07-20 | PXD029353 | Pride
Noble gases Protein stability Sprox Limited proteolysis 
GenomicsAuthentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1
Whole genome sequencing (WGS) from snap-frozen oesophageal tumour tissue and germline nucleic acids isolated from peripheral blood mononuclear cells (PBMC) was performed as part of the International Cancer Genome Consortium project and OCCAMS consortium (1,2). Filtered read sequences were mapped to ...
ORGANISM(S): Homo sapiens 
2016-09-09 | E-MTAB-4600 | biostudies-arrayexpress
ProteomicsLarge-Scale Analysis of Breast Cancer-Related Conformational Changes in Proteins using Limited Proteolysis
Conformational changes in proteins can lead to disease. Thus, methods for identifying conformational changes in proteins can further improve our understanding and facilitate detection of disease states. Here we combine limited proteolysis (LiP) with Stable Isotope Labeling with Amino Acids in Cell ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080770 | MassIVE
ProteomicsGlobal Analysis of Protein Folding Thermodynamics for Disease State Characterization, MCF7 vs MDAMB231
Protein biomarkers can be used to characterize and diagnose disease states such as cancer. They can also serve as therapeutic targets. Current methods for protein biomarker discovery, which generally rely on the large-scale analysis of gene and/or protein expression levels, fail to detect protein b...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080761 | MassIVE
ProteomicsGlobal Analysis of Protein Folding Thermodynamics for Disease State Characterization, MCF7 vs MCF10A
Protein biomarkers can be used to characterize and diagnose disease states such as cancer. They can also serve as therapeutic targets. Current methods for protein biomarker discovery, which generally rely on the large-scale analysis of gene and/or protein expression levels, fail to detect protein b...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080760 | MassIVE
MetabolomicsA metabolomic study of adipose tissue in mice with a disruption of the circadian system

Adipose tissue functions in terms of energy homeostasis as a rheostat for blood triglyceride, regulating its concentration, in response to external stimuli. In addition it acts as a barometer to inform the central nervous system of energy levels which can vary dramatically between meals and accor...

2017-10-27 | MTBLS390 | MetaboLights
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