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ProteomicsFMNL2/SRC-mediated androgen receptor translocation into the nucleus promotes enzalutamide resistance of prostate cancer
Enzalutamide, a second-generation androgen receptor (AR) antagonist, has represented the association with improved overall survival in men with prostate cancer (PCa). However, PCa patients receiving enzalutamide will eventually develop resistance through various mechanisms without effective regimens...
ORGANISM(S): Homo sapiens (Human) 
2025-01-13 | PXD059539 | Pride
Ar Fmnl2 Prostate cancer，enzalutamide resistance 
UnknownIdentification of an FMNL2 Interactome by Quantitative Mass Spectrometry.
Not available
S-EPMC11171801 | biostudies-literature
UnknownCharacterization of Diaphanous-related formin FMNL2 in human tissues.
Not available
S-EPMC2912821 | biostudies-literature
UnknownFMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42.
Not available
S-EPMC5575334 | biostudies-literature
UnknownFMNL2/SRC-mediated androgen receptor translocation into the nucleus promotes enzalutamide resistance of prostate cancer.
Not available
S-EPMC11985155 | biostudies-literature
UnknownCooperative assembly of filopodia by the formin FMNL2 and I-BAR domain protein IRTKS.
Not available
S-EPMC9579038 | biostudies-literature
UnknownThe formin FMNL2 plays a role in the response of melanoma cells to substrate stiffness.
Not available
S-EPMC12039054 | biostudies-literature
UnknownA Rac1-FMNL2 signaling module affects cell-cell contact formation independent of Cdc42 and membrane protrusions.
Not available
S-EPMC5868805 | biostudies-literature
UnknownFMNL2 suppresses cell migration and invasion of breast cancer: a reduction of cytoplasmic p27 via RhoA/LIMK/Cofilin pathway.
Not available
S-EPMC8980084 | biostudies-literature
UnknownFMNL2 destabilises COMMD10 to activate NF-κB pathway in invasion and metastasis of colorectal cancer.
Not available
S-EPMC5674093 | biostudies-literature
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