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Neurodegeneration in mitochondrial disorders is considered irreversible because of limited metabolic plasticity in neurons, yet the cell-autonomous implications of mitochondrial dysfunction for neuronal metabolism in vivo are poorly understood. Here, we profiled the cell-specific proteome of Purkinj...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-03 | PXD019690 | Pride
The metabolic plasticity of mitochondria supports cell development and differentiation and ensures cell survival under stress. The peptidase OMA1 regulates mitochondrial morphology and stress signaling and orchestrates tumorigenesis and cell fate decisions in a cell and tissue-specific manner. Here,...
ORGANISM(S): Mus musculus (Mouse) 
2023-04-04 | PXD036595 | Pride
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