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ProteomicsAnalysis of nuclear extracts from E14 mouse embryonic stem cells
Generated nuclear extracts from embryonic stems cells were compared to cytosolic extracts using shotgun proteomics and labe-free-quantitation.
ORGANISM(S): Mus musculus (Mouse) 
2025-01-02 | PXD041753 | Pride
Nuclear extracts Embryonic stem cells Label-free quantitation 
ProteomicsPlacental growth factor mediates pathological uterine vasculature by activating the NFAT5-SGK1 mechano-signaling axis in the endometrium: Implications for pre-eclampsia development.
After menstruation the uterine spiral arteries are repaired through angiogenesis. This process is tightly regulated by the paracrine communication between endometrial stromal cells (EnSCs) and endothelial cells. Any molecular aberration in these processes can lead to complications in pregnancy inclu...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD051697 | Pride
Pre-eclampsia Endometrium Sgk1 Pregnancy Placentation Mechanobiology Plgf 
ProteomicsNeuronal metabolic rewiring promotesresilience to neurodegeneration caused by mitochondrial dysfunction
Neurodegeneration in mitochondrial disorders is considered irreversible because of limited metabolic plasticity in neurons, yet the cell-autonomous implications of mitochondrial dysfunction for neuronal metabolism in vivo are poorly understood. Here, we profiled the cell-specific proteome of Purkinj...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-03 | PXD019690 | Pride
Anaplerosis Labe-free Tmt Purkinje neurons Mitofusin 2 
ProteomicsConstruction of functional tissue-engineered microvasculatures by using circulating fibrocytes as mural cells
Mural cells are essential to the proper function of microvasculatures. However, the feasible cell source for mural cells has not been found, which is one of the key obstacles facedin tissue engineering. Our data show that circulating fibrocytes (CFs) sheathed and stabilized the microvasculatures for...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD006763 | Pride
Tissue-engineered microvasculatures Circulating fibrocyte 
TranscriptomicsNovel Post-radiation Sarcoma Cell Line
A primary human cell line, UACC-SARC1, was derived from a resection for a neoadjuvant chemotherapy resistant radiation induced spindle cell sarcoma. The sarcoma cell line was derived from a breast cancer patient who was treated with breast conserving surgery and radiation therapy. This radiation in...
ORGANISM(S): Homo sapiens 
2012-08-01 | E-MEXP-3419 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of hiPSC stem cell lines.
The Purpose of this series of experiments is to identify copy number variations, duplications, and deletions in human induced pluripotent stem (hiPSC) cell lines. Genomic DNA of different human induced pluripotent stem cell lines are extracted and hybridized to NimbleGen CGH microarray, using genomi...
ORGANISM(S): Homo sapiens 
2012-01-07 | E-GEOD-33484 | biostudies-arrayexpress
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