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MetabolomicsDietary Formate Metabolomics in Malayan Pangolins
Plasma metabolomics and 13C-formate tracing of dietary formate intervention in Malayan pangolins.
2026-08-27 | MTBLS15448 | MetaboLights
MetabolomicsPhotorespiration is linked to DNA methylation by formate as one-carbon source.
DNA methylation is a key epigenetic modification regulating genome organization, stability, and gene expression. Stable DNA methylation critically relies on methyl groups provided through folate-mediated one-carbon (C1) metabolism, yet the origin and regulation of C1 supply remain elusive. Here we d...
2026-01-06 | MTBLS13444 | MetaboLights
TranscriptomicsSteady-state samples of Methanococcus maripaludis MM901 grown on formate under hydrogen limited conditions
Hydrogenotrophic methanogenic Archaea are defined by a H2 requirement for growth. Despite this requirement, many hydrogenotrophs are also capable of growth with formate as an electron donor for methanogenesis. Hydrogenotrophs respond to H2 starvation both phenotypically and at the level of gene expr...
ORGANISM(S): Methanococcus maripaludis S2 
2013-05-03 | E-GEOD-42111 | biostudies-arrayexpress
ProteomicsEngineering a new-to-nature cascade for phosphate-dependent formate to formaldehyde conversion in vitro and in vivo
To realize a carbon-neutral bioeconomy, the concept of electrobiocatalysis has been developed, in which CO2 is first chemically reduced to formate and subsequently assimilated by enzymatic cascades or engineered microbes. A key step in the assimilation of formate is its reduction into formaldehyde, ...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2023-03-22 | MSV000091532 | MassIVE
ProteomicsA Metal-Dependant Formate Dehydrogenase Advances the Formate Bio-economy
In this manuscript a multi-subunit metal dependent FDH is functionally expressed in a strain of E. coli engineered to assimilate all energy and biomass from formate. The replacement of the previously described FDH with this new, faster FDH allows for improved growth parameters rivaling natural forma...
ORGANISM(S): Escherichia coli 
2025-07-14 | PXD059132 | Pride
Isoprenol Mevalonate Jbei Formate dehydrogenase Formate Reductive glycine pathway Bioproducion 
ProteomicsA Metal-Dependant Formate Dehydrogenase Advances the Formate Bio-economy
In this manuscript a multi-subunit metal dependent FDH is functionally expressed in a strain of E. coli engineered to assimilate all energy and biomass from formate. The replacement of the previously described FDH with this new, faster FDH allows for improved growth parameters rivaling natural forma...
ORGANISM(S): Escherichia coli 
2025-06-06 | PXD062361 | Pride
Isoprenol Mevalonate Bakar bioenginuity Formate dehydrogenase Formate Reductive glycine pathway Bioproducion 
ProteomicsFormate-induced phospho-signalling
The mitochondrial serine catabolism to formate induces a metabolic switch to a hypermetabolic state with high rates of glycolysis, purine synthesis and pyrimidine synthesis. While formate is a purine precursor it is not obvious link between formate and pyrimidine synthesis. Methods Here we combine p...
ORGANISM(S): Homo sapiens (Human) 
2020-09-28 | PXD019347 | Pride
Metabolism Formate Phosphoproteomics Ms Cancer 
TranscriptomicsTranscription profiling of E. coli BW25113 fhlAL/pCA24N-FhlA133 vs fhlA/pCA24N-FhlA in modified-complex 20 mM formate at 37A?C
Variant FhlA133 (Q11H, L14V, Y177F, K245R, M288K, and I342F) had eight- fold higher hydrogen production than FhlA wild-type under 30 min of anaerobic incubation in modified-complex 20 mM formate at 37ºC. The mechanism by which the FhlA133 mutations increase hydrogen production is by increasing the ...
ORGANISM(S): Escherichia coli 
2009-12-19 | E-GEOD-13902 | biostudies-arrayexpress
GenomicsEffect of formate on LN229 cells
Effect of formate on LN229 cells
PRJNA806943 | ENA
ProteomicsA quantitative metabolic analysis reveals Acetobacterium woodii as a flexible and robust host for formate-based bioproduction
Cheap and renewable feedstocks such as the one carbon substrate formate are emerging for sustainable production in a growing chemical industry. By quantitatively analyzing physiology, transcriptome, proteome in chemostat cultivations in combination with computational analyses, we investigated the ac...
ORGANISM(S): Acetobacterium woodii 
2023-03-08 | PXD026569 | Pride
Mixed gas fermentation Continuous fermentation Metabolic modelling Substrate co-utilization Acetogens Omics analysis Formate bioeconomy 
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