Sort   by:  
 Page size 
ProteomicsThe E. coli type III secreted effectors NleB and EspL interact with the microtubule associated protein ensconsin to disrupt vesicle trafficking, part 2
This is the companion dataset to PXD002933. This contains additional RAW files
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2016-12-22 | PXD002995 | Pride
Virulence Bacteria Pathogenesis 
ProteomicsThe E. coli type III secreted effectors NleB and EspL interact with the microtubule associated protein ensconsin to disrupt vesicle trafficking, part 1
Enteropathogenic and enterohaemorrhagic E. coli (EPEC and EHEC) translocate a set of type III effector proteins into host cells that are critical for bacterial virulence. These effectors subvert normal host pathways by interacting with a variety of targets within the cell, but the binding partners ...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2016-12-22 | PXD002933 | Pride
Human E. coli Effector Host-pathogen 
ProteomicsPCP SILAC of apoptosis initiation
Protein correlation profiling using size exclusion and blue native page analysis of protein complexes coupled with SILAC to enable the comparsion between conditions
ORGANISM(S): Homo sapiens (Human) 
2017-01-17 | PXD002892 | Pride
Human Apoptosis Jurkat Lc-ms 
ProteomicsCitrobacter rodentium ICC168 CPX SILAC
SILAC experiment to investigate proteome changes in response to the disruption of CPX in Citrobacter rodentium ICC168.
ORGANISM(S): Citrobacter rodentium ICC168 
2019-01-07 | PXD009049 | Pride
Lc-ms Bacterial Silac 
ProteomicsProteomic Investigation of Neurotrophic trans-Banglene Reveals Potential Link to Iron Homeostasis
Neurodegenerative diseases remain an area where the causative disease mechanisms, with few exceptions, are poorly understood and which are very resistant to modern therapeutic advances. Current FDA-approved medications result in modest improvements in quality of life measures and no increase in life...
ORGANISM(S): Rattus Norvegicus (ncbitaxon:10116) 
2024-07-04 | MSV000095252 | MassIVE
ProteomicsProteomics on spermathecal fluid of BC queens
We sampled honey bee queens from beekeepers throughout British Columbia which were rated as either 'failed' or 'healthy' by beekeepers. We performed shot-gun proteomics on the spermathecal fluid (sperm removed). Proteins were reduced, alkylated, and digested with Lys-C for 4 h in urea digestion buff...
ORGANISM(S): Apis Mellifera 
2020-03-04 | MSV000085056 | MassIVE
ProteomicsVarroa destructor LC-MSMS crossing developmental stages and sexes
Varroa destructor is one of the most prevalent and economically damaging honey bee pests worldwide, weakening colonies by simultaneously parasitizing and transmitting damaging viruses. Despite these impacts on honey bee health, surprisingly little is known about its fundamental molecular biology. He...
ORGANISM(S): Varroa destructor 
2017-09-06 | PXD006072 | Pride
Lc-msms Development Protein atlas Varroa destructor 
ProteomicsTowards an upgraded honey bee (Apis mellifera L.) genome annotation using proteogenomics.
The honey bee is a key pollinator in many agricultural operations as well as a model organism for studying the genetics and evolution of social behaviour. The Apis mellifera genome has been sequenced and annotated twice over, enabling proteomics and functional genomics methods for probing relevant a...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) Apis mellifera (Honeybee) Drosophila melanogaster (Fruit fly) Saccharomyces cerevisiae (Baker's yeast) Caenorhabditis elegans 
2016-01-18 | PXD002275 | Pride
Honey bees Proteogenomics Mass spectrometry Gene annotation Apis mellifera 
MetabolomicsA Murine Model of Maternal Micronutrient Deficiencies and Gut Inflammatory Host-microbe Interactions in the Offspring.

BACKGROUND & AIMS: Micronutrient deficiency (MND) (ie, lack of vitamins and minerals) during pregnancy is a major public health concern. Historically, studies have considered micronutrients in isolation; however, MNDs rarely occur alone. The impact of co-occurring MNDs on pu...

2024-10-18 | MTBLS3476 | MetaboLights
ProteomicsRole of the sarcin-ricin loop of 23S rRNA in biogenesis of the 50S ribosomal subunit
In this work, we show that 23S rRNA lacking the SRL can be efficiently reconstituted into 50S subunits, which exhibit full peptidyl transferase (PT) activity. Using cryo-EM and proteomic methods, we also further characterize affinity-purified SRL particles isolated from cells. Collectively, these da...
ORGANISM(S): Escherichia coli 
2025-05-07 | PXD056260 | Pride
Lc-msms Escherichia coli 50s ribosomal subunit Proteomics 
Sort   by:  
 Page size