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UnknownFOXP3 promoter demethylation reveals the committed Treg population in humans.
Not available
S-EPMC2238816 | biostudies-literature
ProteomicsInverted chromatin immunoprecipitation identifies Tcf1 as a negative regulator of Foxp3 expression
Regulatory T (Treg) cells are important regulators of the immune system and have versatile functions for the homeostasis and repair of tissues. They express the forkhead box transcription factor Foxp3 as a lineage-defining protein. In mature Treg cells, the Foxp3 core promoter is unmethylated indica...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-26 | PXD018764 | Pride
T-cell factor 1 (tcf1) Foxp3-promoter Regulatory t (treg) cells 
TranscriptomicsLoss of Foxp3-driven epigenetic modification leads to regulatory T cell insufficiency
Regulatory T cells (Tregs) are responsible for limiting autoimmunity and chronic inflammation. Foxp3 is a transcription factor that acts as a master regulator of Treg development and function. A serendipitous observation led to the realization that a well-characterized Foxp3gfp reporter mouse, whic...
ORGANISM(S): Mus musculus 
2012-12-07 | E-GEOD-35164 | biostudies-arrayexpress
UnknownPhysical activity, black carbon exposure, and DNA methylation in the FOXP3 promoter.
Not available
S-EPMC5470266 | biostudies-literature
UnknownNon-small-cell lung cancer-induced immunosuppression by increased human regulatory T cells via Foxp3 promoter demethylation.
Not available
S-EPMC11028464 | biostudies-literature
UnknownFoxP3 associates with enhancer-promoter loops to regulate Treg-specific gene expression.
Not available
S-EPMC9059705 | biostudies-literature
UnknownOestrogen Receptor-α binds the FOXP3 promoter and modulates regulatory T-cell function in human cervical cancer.
Not available
S-EPMC5725534 | biostudies-literature
UnknownDNMT1-mediated Foxp3 gene promoter hypermethylation involved in immune dysfunction caused by arsenic in human lymphocytes.
Not available
S-EPMC7467266 | biostudies-literature
UnknownTGF-beta and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3.
Not available
S-EPMC2544572 | biostudies-literature
UnknownG allele at -924 A > G position of FoxP3 gene promoter as a risk factor for tuberculosis.
Not available
S-EPMC5637085 | biostudies-literature
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