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TranscriptomicsThe Forkhead factor FoxQ1 influences epithelial differentiation
The Forkhead family of transcription factors comprises numerous members and is implicated in various cellular functions, including cell growth, apoptosis, migration and differentiation.In this study we identified the Forkhead factor FoxQ1 as increased in expression during TGF-beta1 induced changes i...
ORGANISM(S): Mus musculus 
2010-09-01 | E-GEOD-23833 | biostudies-arrayexpress
Proteomicsp53 is a suppressor of the carcinoma-associated transcription factor FOXQ1
FOXQ1 transcription factors is highly induced in several types of carcinomas where it promotes tumour growth and metastasis, however, the molecular mechanisms leading to FOXQ1 deregulation in cancer are incompletely understood. Here, we used a CRISPR/Cas9-based genomic locus proteomics (GLoPro) to ...
ORGANISM(S): Homo sapiens (Human) 
2024-05-13 | PXD047868 | Pride
Foxq1 P53 Glopro Cancer Transcription factor 
TranscriptomicsRNA-seq of FOXQ1-transfected HCT116 cells to understand the Wnt-dependent and independent FOXQ1 transcriptional output in colorectal cancers.
FOXQ1 is a putative oncogene in several types of carcinomas and, in colorectal cancers, is one of the most highly upregulated genes. FOXQ1 has been previously identified as a candidate Wnt pathway activator in CRC cells. However, it is still unclear how the crosstalk between FOXQ1 and Wnt signalling...
ORGANISM(S): Homo sapiens 
2022-09-23 | E-MTAB-12062 | biostudies-arrayexpress
ProteomicsThe oncogene FOXQ1 is a selective activator of Wnt/β-catenin signalling
The forkhead box transcription factor FOXQ1 is aberrantly induced in various cancers, and contributes to tumour growth and metastasis. It has been suggested that the oncogenic potential of FOXQ1 may be explained by its activation of the Wnt/β-catenin signalling pathway.However, the mode of action of...
ORGANISM(S): Homo sapiens (Human) 
2022-10-05 | PXD030464 | Pride
Human Lc-msms 
ProteomicsThe oncogenic transcription factor FOXQ1 is a bimodal regulator of Wnt target genes
The forkhead box transcription factor FOXQ1 is aberrantly induced in various cancers, and contributes to tumour growth and metastasis. It has been suggested that the oncogenic potential of FOXQ1 may be explained by its activation of the Wnt/β-catenin signalling pathway. However, the mode of action ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-05 | PXD035624 | Pride
Human Lc ms/ms Hek293t 
GenomicsRNA-seq of FOXQ1-transfected HCT116 cells to understand the Wnt-dependent and independent FOXQ1 transcriptional output in colorectal cancers.
RNA-seq of FOXQ1-transfected HCT116 cells to understand the Wnt-dependent and independent FOXQ1 transcriptional output in colorectal cancers.
PRJEB55497 | ENA
ProteomicsThe potential binding proteins of FOXQ1 were detected by mass spectrometry technology, laying the foundation for the subsequent in-depth study of its molecular mechanism
First, Flag-FOXQ1 was overexpressed in HCT-116 cells. Subsequently, the Flag-FOXQ1 complex was enriched via immunoprecipitation (IP) technology. The complex was then washed four times with phosphate-buffered saline (PBS), denatured in loading buffer by boiling, and separated via gel electrophoresis ...
ORGANISM(S): Homo Sapiens 
2025-06-09 | PXD064807 |
GenomicsFOXQ1 is a critical regulator of the mammary epithelial to mesenchymal transcription program
FOXQ1 is a critical regulator of the mammary epithelial to mesenchymal transcription program
PRJNA593005 | ENA
TranscriptomicsThe Forkhead factor FoxQ1 influences epithelial differentiation
The Forkhead family of transcription factors comprises numerous members and is implicated in various cellular functions, including cell growth, apoptosis, migration and differentiation.In this study we identified the Forkhead factor FoxQ1 as increased in expression during TGF-beta1 induced changes i...
ORGANISM(S): Mus musculus 
2010-09-01 | GSE23833 | GEO
GenomicsFOXQ1 Regulates Mitochondrial Cristae Formation and Energy Metabolism in Mouse Brain Endothelial Cells [CUT&TAG]
FOXQ1 Regulates Mitochondrial Cristae Formation and Energy Metabolism in Mouse Brain Endothelial Cells [CUT&TAG]
PRJNA1133709 | ENA
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