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MetabolomicsLC-MS/MS metabolomics unravels the resistant phenotype of carbapenemase-producing Enterobacteriaceae

Introduction: The degree of antimicrobial resistance demonstrated by carbapenemase-producing Enterobacteriaceae (CPE) represents a growing public health challenge. Conventional methods for detecting CPE involve culture-based techniques with lengthy incubation steps. There is a ne...

2025-08-04 | MTBLS10129 | MetaboLights
UnknownRituximab extended schedule or re-treatment trial for low-tumor burden follicular lymphoma: eastern cooperative oncology group protocol e4402.
Not available
S-EPMC4171355 | biostudies-literature
MetabolomicsSAR11 Cells Rely on Enzyme Multifunctionality to Transport and Metabolize a Range of Polyamine Compounds
In the ocean surface layer and cell culture, the polyamine transport protein PotD of SAR11 bacteria is often one of the most abundant proteins detected. Polyamines are organic cations at seawater pH produced by all living organisms and are thought to be an important component of dissolved organic ma...
2021-09-09 | MTBLS3146 | MetaboLights
UnknownVaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma.
Not available
S-EPMC3139394 | biostudies-literature
MetabolomicsLeucine degradation metabolite ratio as a measure of meropenem susceptibility in carbapenem-resistant Klebsiella pneumoniae

Rapid detection of carbapenem-resistant Klebsiella pneumoniae (CRKP) is essential for effective clinical management and surveillance. This study investigated volatile organic compounds (VOCs) as phenotypic biomarkers of carbapenem resistance, with the goal of developing a translationally...

2026-06-09 | MTBLS13539 | MetaboLights
ProteomicsChemotherapy-induced cellular senescence is characterized by aberrant lipid regulation and lipid peroxidation
As normal cells approach their proliferative limit, they arrest to undergo replicative senescence, displaying large cell size, flat morphology and activation of senescence-associated beta-galactosidase (SA-b-Gal). A subset of normal or tumor cells exposed in vitro or in vivo to chemotherapy agents s...
ORGANISM(S): Mus musculus (Mouse) 
2017-11-06 | PXD006216 | Pride
Maxquant lfq Lipid peroxidation Mus Q-exactive Chemotherapy-induced senescence Quant proteomics 
ProteomicsIsolation and characterization of multi-protein complexes enriched in the K-Cl co-transporter 2 from brain plasma membranes
Kcc2 plays a critical role in determining the efficacy of synaptic inhibition, however, the cellular mechanism neurons use to regulate its membrane trafficking, stability and activity are ill-defined. To address these issues, we used affinity purification to isolate stable multi-protein complexes of...
ORGANISM(S): Mus musculus (Mouse) 
2020-10-22 | PXD021368 | Pride
Kcc2 Phosphorylation Proteome Interactome 
OtherQuantitative proteomics analysis of the Arg/N-end rule pathway of targeted degradation in Arabidopsis roots.
Data from ProteomeXchange, PXD ID: PXD001719. Experiment: TAILS_freeNt, file: TAILS_B_freeNt.msf.mgf. Published as part of Proteomics. 2015 Feb 27 . From the Abstract: {{i}} According to the Arg/N-end rule pathway, proteins with basic N-termini are targeted for degradation by the Arabidopsis thalia...
ORGANISM(S): Ath1 
GPM32320014396 | GPMDB
Resource Reanalysis 
UnknownMajor Histocompatibility Complex Class II and Programmed Death Ligand 1 Expression Predict Outcome After Programmed Death 1 Blockade in Classic Hodgkin Lymphoma.
Not available
S-EPMC5877802 | biostudies-literature
ProteomicsThe Quantitative Changes in the Yeast Hsp70 and Hsp90 Interactomes upon DNA Damage
The molecular chaperones Hsp70 and Hsp90 participate in many important cellular processes, including how cells respond to DNA damage. In this study, we applied quantitative affinity-purification mass spectrometry (AP-MS) proteomics to understand the protein network through which Hsp70 and Hsp90 exe...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2014-12-08 | PXD001284 | Pride
Saccharomyces cerevisiae 18o quantitation Ltq orbitrap xl Lc-ms/ms 
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