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ProteomicsATR inhibition rewires cellular signaling networks in response to pathologic replication stress
DNA replication stress is the major cause of genomic instability in human cells. The ataxia telangiectasia and Rad3-related kinase (ATR) plays an essential role in the cellular response to replication stress and inhibition of ATR has emerged as therapeutic strategy for the treatment of cancer. Howev...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080795 | MassIVE
ProteomicsAssessing Customized Multivalent Chemokine-Binding Peptide Treatment in a Murine Model of Coxsackievirus B3 Infection
This study investigates the therapeutic potential of BK1.3, a synthetic Evasin-derived peptide, in a murine model of Coxsackievirus B3 (CVB3)-induced viral myocarditis. Myocarditis, an inflammatory disease of the heart muscle, is often triggered by viral infections and driven by excessive immune cel...
ORGANISM(S): Mus musculus (Mouse) Coxsackievirus 
2025-05-07 | PXD060461 | Pride
Infection Inflammation Liver metabolism Evasin Chemokines Coxsackievirus b3 
ProteomicsA renal function for 2,3-bisphosphoglycerate mutase (BPGM)
The enzyme 2,3 bisphosphoglycerate mutase (BPGM) catalyzes the production of 2,3-bisphosphoglycerate (2,3-BPG). The main role of 2,3-BPG is to shift the equilibrium of hemoglobin toward the deoxy-state, accounting for the notion that 2,3-BPG production would appear to be solely useful in cells which...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD040789 | Pride
Metabolism Nephron Reactive oxygen species (ros) Kidney Bpgm Acute kidney injury (aki) Apoptosis 
ProteomicsMechanistic Insights Into Postoperative Delirium Using Untargeted High-Throughput Proteomics in Elderly Patients – A Case-Control Study
This dataset is part of the European BioCog project (EU602461) and comprises perioperative plasma samples from elderly patients (≥65 years) undergoing elective surgery. Proteomic profiling was conducted in a matched case-control design to investigate molecular mechanisms of postoperative delirium (P...
ORGANISM(S): Homo sapiens (Human) 
2026-02-16 | PXD071265 | Pride
Proteomics3T3_L1_RAW_bilayer2_2
3T3-L1 preadipocytes and RAW 264.7 macrophages bilayer; Silac labeled; Replicate 2, sample 2
ORGANISM(S): Mus Musculus 
2013-12-31 | PAe005149 | PeptideAtlas
Proteomics3T3_L1_RAW_bilayer_Phospho
3T3-L1 preadipocytes and RAW 264.7 macrophages bilayer; Silac labeled; Phosphopeptide enrichment
ORGANISM(S): Mus Musculus 
2013-12-31 | PAe005148 | PeptideAtlas
ProteomicsMm_macrophages_phospho_silac
RAW 264.7 macrophages monolayer; Silac labeled; Phosphopeptide enrichment, Sample 2
ORGANISM(S): Mus Musculus 
2013-12-31 | PAe005147 | PeptideAtlas
ProteomicsMm_macrophages_silac_R2
RAW 264.7 macrophages monolayer; Silac labeled; Replicate 2
ORGANISM(S): Mus Musculus 
2013-12-31 | PAe005145 | PeptideAtlas
Proteomics3T3_L1_RAW_bilayer1
3T3-L1 preadipocytes and RAW 264.7 macrophages bilayer; Silac labeled; Replicate 1
ORGANISM(S): Mus Musculus 
2013-12-31 | PAe005144 | PeptideAtlas
Proteomics3T3_L1_only_Phospho
3T3-L1 preadipocytes monolayer; Silac labeled; Phosphopeptide enrichment
ORGANISM(S): Mus Musculus 
2013-12-31 | PAe005143 | PeptideAtlas
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