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TranscriptomicsVitamin D receptor (VDR) regulates epidermal stem cells and cutanous wound healing [keratinocytes]
The vitamin D receptor (VDR) regulates cell proliferation and differentiation including epidermal keratinocytes by modulating transcription of its target genes. We are investigating the role of VDR in epidermal stem cells and their progenies in the regeneration process of epidermis and hair in the s...
ORGANISM(S): Mus musculus 
2015-07-31 | E-GEOD-68729 | biostudies-arrayexpress
MetabolomicsComparison of singlequad and Orbitrap mass analyzer coupled to gas chromatography reveals potential of high resolution GC MS for untargeted metabolomics

The development of improved spectrometers and supporting computational tools is expected to eventually enable the rapid annotation of whole metabolomes. However, rarely are novel mass spectrometers directly compared to the previously used ones in the field of metabolomics, thus preventing researc...

2020-01-24 | MTBLS1104 | MetaboLights
UnknownAdjuvant Chemoradiotherapy With Epirubicin, Cisplatin, and Fluorouracil Compared With Adjuvant Chemoradiotherapy With Fluorouracil and Leucovorin After Curative Resection of Gastric Cancer: Results From CALGB 80101 (Alliance).
Not available
S-EPMC5678342 | biostudies-literature
UnknownNut Consumption and Survival in Patients With Stage III Colon Cancer: Results From CALGB 89803 (Alliance).
Not available
S-EPMC5891130 | biostudies-literature
UnknownOxidative cyclization of <i>N</i>-methyl-dopa by a fungal flavoenzyme of the amine oxidase family.
Not available
S-EPMC6222107 | biostudies-literature
TranscriptomicsAblation of coactivator Med1 regulates bulge keratinocyte stem cells and accelerates epidermal regeneration after injury [10wk keratinocyte]
Transcriptional coactivator Mediator complex facilitates transcription of various transcription factors. Previously, we have generated Med1 conditional null mice, where a critical subunit of Mediator, Med1, is removed from keratinocytes. Here we present evidence that ablation of Med1 accelerated epi...
ORGANISM(S): Mus musculus 
2014-01-01 | E-GEOD-50672 | biostudies-arrayexpress
TranscriptomicsType I Interferons Control Proliferation and Function of Intestinal Epithelium
Wnt pathway-driven proliferation and renewal of the intestinal epithelium must be tightly controlled to prevent development of cancer and barrier dysfunction. Although type 1 interferons (IFN) produced in the gut under influence of microbiota are known for their anti-proliferative effects, the role ...
ORGANISM(S): Mus musculus 
2016-01-05 | E-GEOD-76512 | biostudies-arrayexpress
TranscriptomicsInactivation of interferon signaling promotes the establishment of an immunosuppressive microenvironment in colorectal cancers
Tumors arise and grow despite anti-cancer immune responses. These responses can be stimulated by immunotherapies such as immune checkpoint inhibitors (e.g. anti-PD1 antibodies) and chimeric antigen receptors (CAR). Efficacy of these agents in solid tumors including colorectal cancers (CRC) is limite...
ORGANISM(S): Mus musculus 
2016-01-15 | E-GEOD-76889 | biostudies-arrayexpress
ProteomicsIdentification of ETV6 bound protein by affinity purification of ETV6-HA fusion protein in REH cells
To determine the protein partners of ETV6, we expressed ETV6 and HA-tagged ETV6 in Reh pre-B leukemic cells. Anti-HA magnetic beads were used for affinity purification of ETV6-HA (and ETV6 control) from the nuclear and cytoplasmic fraction. Following purification on-beads digest and LC-MS/MS experim...
ORGANISM(S): Homo sapiens (Human) 
2022-01-26 | PXD031001 | Pride
Leukemia All Etv6 
TranscriptomicsAblation of coactivator Med1 regulates bulge keratinocyte stem cells and accelerates epidermal regeneration after injury.
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2014-01-01 | E-GEOD-50673 | biostudies-arrayexpress
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